(Q33654425)

28 July 2017

Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH. (English)

1 reference

28 July 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28474685%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Matthew J Whitley

2

1 reference

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9 June 2020

Patrick van der Wel

5

1 reference

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9 June 2020

author name string

Mingyue Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28474685%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Angela M Gronenborn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28474685%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

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publication date

5 May 2017

1 reference

28 July 2017

Nature Communications

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9 June 2020

volume

8

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9 June 2020

page(s)

15137

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Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

5 May 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms15137

0 references

cites work

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Single-molecule Force Spectroscopy Predicts a Misfolded, Domain-swapped Conformation in human γD-Crystallin Protein

21 June 2018

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21 June 2018

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Structural changes and proapoptotic peroxidase activity of cardiolipin-bound mitochondrial cytochrome c

21 June 2018

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21 June 2018

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Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients

21 June 2018

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Comparative analysis of human γD-crystallin aggregation under physiological and low pH conditions

21 June 2018

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Physical and structural basis for polymorphism in amyloid fibrils

21 June 2018

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Amyloid fiber formation in human γD-Crystallin induced by UV-B photodamage

21 June 2018

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Crystal structure of the cataract-causing P23T γD-crystallin mutant

21 June 2018

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ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

21 June 2018

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The Human W42R D-Crystallin Mutant Structure Provides a Link between Congenital and Age-related Cataracts

21 June 2018

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Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation

21 June 2018

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Cataract-causing defect of a mutant γ-crystallin proceeds through an aggregation pathway which bypasses recognition by the α-crystallin chaperone

21 June 2018

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Chaperone networks in protein disaggregation and prion propagation

21 June 2018

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Protein misfolding and aggregation in cataract disease and prospects for prevention

21 June 2018

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21 June 2018

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Two-dimensional IR spectroscopy and segmental 13C labeling reveals the domain structure of human γD-crystallin amyloid fibrils

21 June 2018

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The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug

21 June 2018

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21 June 2018

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Amyloid-like fibrils from a domain-swapping protein feature a parallel, in-register conformation without native-like interactions.

21 June 2018

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Aggregation of γ-crystallins associated with human cataracts via domain swapping at the C-terminal β-strands

21 June 2018

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The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils

21 June 2018

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Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

21 June 2018

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SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

21 June 2018

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Abeta(1-40) forms five distinct amyloid structures whose beta-sheet contents and fibril stabilities are correlated

21 June 2018

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Increase in surface hydrophobicity of the cataract-associated P23T mutant of human gammaD-crystallin is responsible for its dramatically lower, retrograde solubility.

21 June 2018

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Conformational flexibility of Y145Stop human prion protein amyloid fibrils probed by solid-state nuclear magnetic resonance spectroscopy

21 June 2018

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21 June 2018

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21 June 2018

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The Structure of the Cataract-Causing P23T Mutant of Human γD-Crystallin Exhibits Distinctive Local Conformational and Dynamic Changes † , ‡

21 June 2018

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Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy

21 June 2018

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Genetics of crystallins: cataract and beyond.

21 June 2018

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Crystallin proteins and amyloid fibrils

21 June 2018

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Formation of amyloid fibrils in vitro by human gammaD-crystallin and its isolated domains.

21 June 2018

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Altered phase diagram due to a single point mutation in human gammaD-crystallin

21 June 2018

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Protein misfolding, functional amyloid, and human disease

21 June 2018

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The CCPN data model for NMR spectroscopy: development of a software pipeline

21 June 2018

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Ageing and vision: structure, stability and function of lens crystallins

21 June 2018

1 reference

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High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract

21 June 2018

1 reference

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21 June 2018

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Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

21 June 2018

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21 June 2018

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Cataract as a protein condensation disease: the Proctor Lecture.

21 June 2018

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21 June 2018

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Protein interactions in the calf eye lens: interactions between beta-crystallins are repulsive whereas in gamma-crystallins they are attractive

21 June 2018

1 reference

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Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation

21 June 2018

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The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin.

21 January 2018

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Decrease in protein solubility and cataract formation caused by the Pro23 to Thr mutation in human gamma D-crystallin

21 January 2018

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Structural studies reveal that the diverse morphology of beta(2)-microglobulin aggregates is a reflection of different molecular architectures.

21 January 2018

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An alternative structural isoform in amyloid-like aggregates formed from thermally denatured human γD-crystallin.

21 January 2018

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Cataract-linked mutation R188H promotes βB2-crystallin aggregation and fibrillization during acid denaturation.

21 January 2018

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In vitro unfolding, refolding, and polymerization of human gammaD crystallin, a protein involved in cataract formation

21 January 2018

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Further conventions for NMR shielding and chemical shifts (IUPAC Recommendations 2008).

21 January 2018

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Enhancement of nuclear magnetic resonance signals by polarization transfer

21 January 2018

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Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins

21 January 2018

1 reference

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On the use of ultracentrifugal devices for routine sample preparation in biomolecular magic-angle-spinning NMR.

21 January 2018

1 reference

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The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client.

30 October 2018

1 reference

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Preparation of protein nanocrystals and their characterization by solid state NMR

30 October 2018

1 reference

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Short-range order of crystallin proteins accounts for eye lens transparency

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15137

Direct measurement of pH in the rat lens by ion-sensitive microelectrodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15137

inferred from DOI database lookup

7 January 2021

based on heuristic

Assessing polyglutamine conformation in the nucleating event by molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15137

inferred from DOI database lookup

7 January 2021

based on heuristic

Cross polarization in the tilted frame: assignment and spectral simplification in heteronuclear spin systems

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15137

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS15137

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28474685%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

ADS bibcode

2017NatCo...815137B

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28474685%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference