(Q33661711)

28 July 2017

Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3. (English)

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28 July 2017

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1 reference

5

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28 July 2017

6

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28 July 2017

Mark W Robinson

4

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Sheila M Donnelly

object named as

Sheila Donnelly

1

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author name string

Sandra M O'Neill

2

1 reference

28 July 2017

Colin M Stack

3

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28 July 2017

John P Dalton

7

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28 July 2017

language of work or name

English

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publication date

18 November 2009

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Journal of Biological Chemistry

28 July 2017

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28 July 2017

285

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28 July 2017

5

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28 July 2017

3383-3392

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The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling.

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Helminth pathogen cathepsin proteases: it's a family affair.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Dynamics of lung macrophage activation in response to helminth infection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Bromelain inhibits lipopolysaccharide-induced cytokine production in human THP-1 monocytes via the removal of CD14.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Structural and Functional Relationships in the Virulence-associated Cathepsin L Proteases of the Parasitic Liver Fluke, Fasciola hepatica

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Update on toll-like receptor-directed therapies for human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Chronic helminth infections may negatively influence immunity against tuberculosis and other diseases of public health importance.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Chronic helminth infections induce immunomodulation: consequences and mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Helminths as governors of immune-mediated inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

The role of cystatins in cells of the immune system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

The immunobiology of Th1 polarization in high-pathology schistosomiasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Toll-like receptor signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

The immunobiology of schistosomiasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Cysteine proteases of parasitic organisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Fasciola hepatica suppresses a protective Th1 response against Bordetella pertussis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Proteinases and associated genes of parasitic helminths

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823461

Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Fasciola hepatica: parasite-secreted proteinases degrade all human IgG subclasses: determination of the specific cleavage sites and identification of the immunoglobulin fragments produced.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Fasciola hepatica infection downregulates Th1 responses in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Fasciola hepatica cathepsin L cysteine proteinase suppresses Bordetella pertussis-specific interferon-gamma production in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

De-glycosylation of Pichia pastoris-produced Schistosoma mansoni cathepsin B eliminates non-specific reactivity with IgG in normal human serum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

IRF-3-dependent and augmented target genes during viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: a Leu-12 to Pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular eve

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.060368

Proteolysis of human monocyte CD14 by cysteine proteinases (gingipains) from Porphyromonas gingivalis leading to lipopolysaccharide hyporesponsiveness

21 January 2018

1 reference

12 December 2020

Suppression of macrophage interleukin-12 and tumour necrosis factor-alpha production in mice infected with Toxocara canis

1 reference

12 December 2020

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

12 December 2020

Cysteinyl proteinases of Schistosoma mansoni eggs: purification and partial characterization

1 reference

12 December 2020

Fasciola hepatica: A secreted cathepsin L-like proteinase cleaves host immunoglobulin

1 reference

12 December 2020

Cellular responses during liver fluke infection in sheep and its evasion by the parasite

1 reference

12 December 2020

IL-4R signaling is required to induce IL-10 for the establishment of T(h)2 dominance

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.060368

1 reference

28 July 2017

1 reference

28 July 2017

1 reference