(Q33670439)

28 July 2017

title

Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans (English)

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28 July 2017

main subject

Caenorhabditis elegans

0 references

1 reference

1 reference

1 reference

6

Krzysztof Palczewski

1 reference

28 July 2017

Pengxiu Cao

1

1 reference

28 July 2017

Yiyuan Yuan

2

1 reference

28 July 2017

Elizabeth A Pehek

3

1 reference

28 July 2017

Alex R Moise

4

1 reference

28 July 2017

Ying Huang

5

1 reference

28 July 2017

Zhaoyang Feng

7

1 reference

28 July 2017

language of work or name

English

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publication date

19 February 2010

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28 July 2017

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28 July 2017

volume

5

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28 July 2017

issue

2

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28 July 2017

page(s)

e9312

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

19 February 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Altered vesicular dopamine storage in Parkinson's disease: a premature demise

21 June 2018

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Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice

21 June 2018

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Identification by machine vision of the rate of motor activity decline as a lifespan predictor in C. elegans

21 June 2018

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

21 June 2018

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Tyramine and octopamine independently inhibit serotonin-stimulated aversive behaviors in Caenorhabditis elegans through two novel amine receptors.

21 June 2018

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21 June 2018

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Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration

21 June 2018

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

21 June 2018

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A C. elegans model of nicotine-dependent behavior: regulation by TRP-family channels

21 June 2018

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Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

21 June 2018

1 reference

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Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

21 June 2018

1 reference

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

21 June 2018

1 reference

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A C. elegans stretch receptor neuron revealed by a mechanosensitive TRP channel homologue

21 June 2018

1 reference

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Dopamine in neurotoxicity and neuroprotection: what do D2 receptors have to do with it?

21 June 2018

1 reference

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Molecular pathophysiology of Parkinson's disease

21 June 2018

1 reference

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Automatic tracking, feature extraction and classification of C elegans phenotypes

21 June 2018

1 reference

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The unfolded protein response regulates glutamate receptor export from the endoplasmic reticulum

21 June 2018

1 reference

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Genetic clues to the pathogenesis of Parkinson's disease

21 June 2018

1 reference

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Attenuation of dopamine transporter activity by alpha-synuclein

21 June 2018

1 reference

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Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

21 June 2018

1 reference

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Neuroprotective and neurorestorative strategies for Parkinson's disease

21 June 2018

1 reference

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Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

21 June 2018

1 reference

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Regulation of sex-specific differentiation and mating behavior in C. elegans by a new member of the DM domain transcription factor family

21 June 2018

1 reference

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Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824852

C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824852

A Drosophila model of Parkinson's disease

21 June 2018

1 reference

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Patterning of dopaminergic neurotransmitter identity among Caenorhabditis elegans ray sensory neurons by a TGFbeta family signaling pathway and a Hox gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824852

The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons

21 June 2018

1 reference

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The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors

21 June 2018

1 reference

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21 June 2018

1 reference

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21 June 2018

1 reference

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21 June 2018

1 reference

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Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Pharmacological prevention of Parkinson disease in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Selective loss of dopaminergic neurons and formation of Lewy body-like aggregations in alpha-synuclein transgenic fly neuronal cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

Neurobiology of the Caenorhabditis elegans genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0009312

The C. elegans POU-domain transcription factor UNC-86 regulates the tph-1 tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824852

Alpha-synuclein overexpression increases cytosolic catecholamine concentration

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20174477

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20174477

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetics of Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20174477

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0009312

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference