(Q33676752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

Subhash C. Lakhotia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

author name string

Pankaj Kumar Singh

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

Rashmi Parihar

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

Vibha Dwivedi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

Subramaniam Ganesh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

language of work or name

English

0 references

publication date

19 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

11 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

volume

289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

page(s)

13543-13553

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4036360/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Functional interaction between autophagy and ciliogenesis

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Expanded polyglutamine-containing N-terminal huntingtin fragments are entirely degraded by mammalian proteasomes

21 June 2018

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O-GlcNAc cycling: a link between metabolism and chronic disease

21 June 2018

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Protein truncation as a common denominator of human neurodegenerative foldopathies

21 June 2018

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Impact of O-GlcNAc on cardioprotection by remote ischaemic preconditioning in non-diabetic and diabetic patients

21 June 2018

1 reference

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O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation.

21 June 2018

1 reference

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O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases

21 June 2018

1 reference

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Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart

21 June 2018

1 reference

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In vivo effects of traditional Ayurvedic formulations in Drosophila melanogaster model relate with therapeutic applications

21 June 2018

1 reference

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Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Huntington disease and the huntingtin protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Protein O-GlcNAcylation: A critical regulator of the cellular response to stress.

21 June 2018

1 reference

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Modifiers and mechanisms of multi-system polyglutamine neurodegenerative disorders: lessons from fly models.

21 June 2018

1 reference

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Protein quality control mechanisms and neurodegenerative disorders: Checks, balances and deadlocks

21 June 2018

1 reference

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Methods in mammalian autophagy research

21 June 2018

1 reference

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RNAi for the large non-coding hsromega transcripts suppresses polyglutamine pathogenesis in Drosophila models

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Nutrient-dependent regulation of autophagy through the target of rapamycin pathway.

21 June 2018

1 reference

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The hexosamine biosynthesis inhibitor azaserine prevents endothelial inflammation and dysfunction under hyperglycemic condition through antioxidant effects

21 June 2018

1 reference

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The insulin paradox: aging, proteotoxicity and neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Protein ubiquitination is modulated by O-GlcNAc glycosylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Clearance of mutant aggregate-prone proteins by autophagy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Autophagy: process and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy

21 June 2018

1 reference

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Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications

21 June 2018

1 reference

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The hexosamine signaling pathway: deciphering the "O-GlcNAc code"

21 June 2018

1 reference

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Normal huntingtin function: an alternative approach to Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

O-GlcNAc modification of nucleocytoplasmic proteins and diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Inefficient degradation of truncated polyglutamine proteins by the proteasome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

O-GlcNAc modification is an endogenous inhibitor of the proteasome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Impairment of the ubiquitin-proteasome system by protein aggregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Glycosylation sites flank phosphorylation sites on synapsin I: O-linked N-acetylglucosamine residues are localized within domains mediating synapsin I interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Cytoplasmic O-GlcNAc modification of the head domain and the KSP repeat motif of the neurofilament protein neurofilament-H

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

O-linked N-acetylglucosamine is upregulated in Alzheimer brains.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Pseudopupil phenomena in the compound eye of drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Cleavage pattern and emerging asymmetry of the mouse embryo.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.553321

Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.553321

The malin-laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.553321

Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.553321

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.553321

Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.553321

UDP-N-acetylglucosaminyl transferase (OGT) in brain tissue: temperature sensitivity and subcellular distribution of cytosolic and nuclear enzyme

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036360

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24648514

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased glucose concentration results in reduced proteasomal activity and the formation of glycogen positive aggresomal structures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24648514

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.553321

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24648514%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

PubMed publication ID

24648514

1 reference