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USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy.
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Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
title
USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
main subject
gluconeogenesis
1 reference
based on heuristic
inferred from title
hepatic gluconeogenesis
1 reference
based on heuristic
inferred from title
author
Joseph T Rodgers
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
author name string
Jessica A Hall
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Mitsuhisa Tabata
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Pere Puigserver
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
publication date
2 April 2014
1 reference
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Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
published in
Molecular Endocrinology
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
volume
28
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
page(s)
912-924
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity.
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21 June 2018
Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects
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ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage
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Hepatic Suppression of Foxo1 and Foxo3 Causes Hypoglycemia and Hyperlipidemia in Mice
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The Multifaceted Roles of USP7: New Therapeutic Opportunities
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Inhibition of IkappaB kinase alpha (IKKα) or IKKbeta (IKKβ) plus forkhead box O (Foxo) abolishes skeletal muscle atrophy.
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TSPYL5 suppresses p53 levels and function by physical interaction with USP7
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21 June 2018
Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
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21 June 2018
Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.
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21 June 2018
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Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment
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21 June 2018
The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors
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21 June 2018
Mdm2 induces mono-ubiquitination of FOXO4
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21 June 2018
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
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21 June 2018
Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure
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21 June 2018
Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization
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Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.
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21 June 2018
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21 June 2018
FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction
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21 June 2018
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
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21 June 2018
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
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21 June 2018
The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription
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GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7
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21 June 2018
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
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21 June 2018
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation
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21 June 2018
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
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21 June 2018
HAUSP is required for p53 destabilization
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21 June 2018
A dynamic role of HAUSP in the p53-Mdm2 pathway
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21 June 2018
Insulin Inhibition of Transcription Stimulated by the Forkhead Protein Foxo1 Is Not Solely due to Nuclear Exclusion
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21 June 2018
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
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21 June 2018
Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice
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21 June 2018
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
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21 June 2018
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding
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21 June 2018
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
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21 June 2018
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
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21 June 2018
Role of AMP-activated protein kinase in mechanism of metformin action
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21 June 2018
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
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21 June 2018
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
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21 June 2018
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
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21 June 2018
Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence
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21 June 2018
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
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21 June 2018
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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21 June 2018
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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21 June 2018
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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21 June 2018
A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein
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21 June 2018
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer
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21 June 2018
The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids
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21 June 2018
Functional analysis of glucocorticoid and insulin response sequences in the rat insulin-like growth factor-binding protein-1 promoter
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21 June 2018
Cyclic AMP-dependent protein kinase regulates transcription of the phosphoenolpyruvate carboxykinase gene but not binding of nuclear factors to the cyclic AMP regulatory element
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PubMed Central
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21 June 2018
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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30 October 2018
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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30 October 2018
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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30 October 2018
Negative regulation of the forkhead transcription factor FKHR by Akt.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
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30 October 2018
Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042075
retrieved
30 October 2018
Identifiers
DOI
10.1210/ME.2013-1420
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PMC publication ID
4042075
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed publication ID
24694308
1 reference
stated in
Europe PubMed Central
PMC publication ID
4042075
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694308%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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