(Q33716356)

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The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 July 2017

The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

based on heuristic

inferred from title

Nosratola D Vaziri

3

object named as

Nosratola D Vaziri

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Mohammad A Aminzadeh

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Scott A Reisman

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Mahyar Khazaeli

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Jun Yuan

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Colin J Meyer

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

0 references

publication date

6 November 2013

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

570-578

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Rationale and trial design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: the Occurrence of Renal Events (BEACON).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Triterpenoid dihydro-CDDO-trifluoroethyl amide protects against maladaptive cardiac remodeling and dysfunction in mice: a critical role of Nrf2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Curcumin induces Nrf2 nuclear translocation and prevents glomerular hypertension, hyperfiltration, oxidant stress, and the decrease in antioxidant enzymes in 5/6 nephrectomized rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Bardoxolone methyl decreases megalin and activates nrf2 in the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Bardoxolone methyl and kidney function in CKD with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

When NRF2 talks, who's listening?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Oxidative stress and antioxidant treatment in hypertension and the associated renal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Lipid peroxides in atherosclerotic diseases (author's transl)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

21 June 2018

Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Chronic inhibition of nuclear factor-kappaB attenuates renal injury in the 5/6 renal ablation model.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Curcumin ameliorates renal failure in 5/6 nephrectomized rats: role of inflammation

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Intra-renal angiotensin II/AT1 receptor, oxidative stress, inflammation, and progressive injury in renal mass reduction

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Enhanced nitric oxide inactivation and protein nitration by reactive oxygen species in renal insufficiency

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Nrf2-deficient female mice develop lupus-like autoimmune nephritis

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Analogs of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.852705

21 January 2018

Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046874

30 October 2018

Attenuation of glomerular injury in diabetic mice with tert-butylhydroquinone through nuclear factor erythroid 2-related factor 2-dependent antioxidant gene activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of intrarenal angiotensin system activation, oxidative stress, inflammation, and impaired nuclear factor-erythroid-2-related factor 2 activity in the progression of focal glomerulosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDDO-9,11-dihydro-trifluoroethyl amide (CDDO-dhTFEA) induces hepatic cytoprotective genes and increases bile flow in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/24195589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/00498254.2013.852705

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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