(Q37101549)

English

Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species

scientific article published on 06 January 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Scott A Reisman

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Ronnie L Yeager

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Masayuki Yamamoto

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Curtis D Klaassen

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

publication date

6 January 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Toxicological Sciences

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

108

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

35-47

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity.

1 reference

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1 reference

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Peroxynitrite detoxification and its biologic implications.

1 reference

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The Nrf2 activator oltipraz also activates the constitutive androstane receptor

1 reference

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PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

1 reference

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Xenobiotic transporters: ascribing function from gene knockout and mutation studies

1 reference

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Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

1 reference

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Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease

1 reference

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Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

1 reference

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Nrf2 as a novel molecular target for chemoprevention

1 reference

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Glutathione transferases

1 reference

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1 reference

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1 reference

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1 reference

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Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

1 reference

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

1 reference

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Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

1 reference

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Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite

1 reference

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1 reference

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Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione

1 reference

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

1 reference

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Regulation of genes encoding NAD(P)H:quinone oxidoreductases

1 reference

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Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

1 reference

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Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.

1 reference

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Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

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Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element

1 reference

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Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

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A multidrug resistance transporter from human MCF-7 breast cancer cells

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1 reference

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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

1 reference

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1 reference

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An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance.

1 reference

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1 reference

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Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations

1 reference

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Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

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The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

12 December 2020

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inferred from PubMed ID database lookup

Glutathione peroxidase and hydroperoxides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

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based on heuristic

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Assays of glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

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based on heuristic

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Induction of hepatic antioxidant enzymes by phenolic acids in rats is accompanied by increased levels of multidrug resistance-associated protein 3 mRNA expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129213

12 December 2020

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Identifiers

10.1093/TOXSCI/KFN267

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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