(Q33718411)

28 July 2017

title

N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathway (English)

1 reference

28 July 2017

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6

Daniel J Drucker

1 reference

28 July 2017

Anita Johswich

1

1 reference

28 July 2017

Christine Longuet

2

1 reference

28 July 2017

Judy Pawling

3

1 reference

28 July 2017

Anas Abdel Rahman

4

1 reference

28 July 2017

Michael Ryczko

5

1 reference

28 July 2017

James W Dennis

7

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28 July 2017

language of work or name

English

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publication date

17 April 2014

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28 July 2017

number of pages

15

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Journal of Biological Chemistry

inferred from page(s)

published in

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28 July 2017

volume

289

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28 July 2017

issue

23

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28 July 2017

page(s)

15927-15941

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4047366/fullTextXML

inferred from PubMed Central ID database lookup

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14 July 2018

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Metabolic manifestations of insulin deficiency do not occur without glucagon action

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis

14 July 2018

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Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport

14 July 2018

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N-glycosylation is critical for the stability and intracellular trafficking of glucose transporter GLUT4

14 July 2018

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Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling

14 July 2018

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Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes.

14 July 2018

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14 July 2018

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The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

14 July 2018

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Elevation of Global O-GlcNAc in rodents using a selective O-GlcNAcase inhibitor does not cause insulin resistance or perturb glucohomeostasis

14 July 2018

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Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice

14 July 2018

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O-GlcNAc signaling: a metabolic link between diabetes and cancer?

14 July 2018

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Insulin-dependent diabetes mellitus in mice does not alter liver heparan sulfate

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Functioning and evolutionary significance of nutrient transceptors.

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

ATP-citrate lyase links cellular metabolism to histone acetylation

14 July 2018

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Insights into the residence in lipid rafts of adenylyl cyclase AC8 and its regulation by capacitative calcium entry

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

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14 July 2018

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Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes

14 July 2018

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Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

14 July 2018

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Targeted glycoproteomic identification of biomarkers for human breast carcinoma.

14 July 2018

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Plasma membrane domain organization regulates EGFR signaling in tumor cells

14 July 2018

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The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation

14 July 2018

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Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.

14 July 2018

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Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

14 July 2018

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Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

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14 July 2018

1 reference

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Mitochondrial dysfunction in the elderly: possible role in insulin resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Glucagon and regulation of glucose metabolism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

International Union of Pharmacology. XXXV. The glucagon receptor family

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Novel receptor partners and function of receptor activity-modifying proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

N-glycosylation and residues Asn805 and Asn890 are involved in the functional properties of type VI adenylyl cyclase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Suppression of tumor growth and metastasis in Mgat5-deficient mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Transcriptional regulation of N-acetylglucosaminyltransferase V by the src oncogene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Transcriptional regulation of the N-acetylglucosaminyltransferase V gene in human bile duct carcinoma cells (HuCC-T1) is mediated by Ets-1.

14 July 2018

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Complex asparagine-linked oligosaccharides in Mgat1-null embryos

14 July 2018

1 reference

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Antibodies against specific extracellular epitopes of the glucagon receptor block glucagon binding

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047366

Hexosamine pathway metabolites enhance protein quality control and prolong life.

14 July 2018

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https://api.crossref.org/works/10.1074%2FJBC.M114.563734

Hepatic glucose sensing via the CREB coactivator CRTC2.

21 January 2018

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N-linked glycosylation of folded proteins by the bacterial oligosaccharyltransferase.

21 January 2018

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Metabolic homeostasis and tissue renewal are dependent on beta1,6GlcNAc-branched N-glycans.

21 January 2018

1 reference

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Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

ADLAPH: A molecular haplotyping method based on allele-discriminating long-range PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

More than one glycan is needed for ER glucosidase II to allow entry of glycoproteins into the calnexin/calreticulin cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563734

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24742675

12 December 2020

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Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24742675

12 December 2020

inferred from PubMed ID database lookup

A tumor-associated glycosylation change in the glucose transporter GLUT1 controlled by tumor suppressor function in human cell hybrids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24742675

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M114.563734

1 reference

28 July 2017

1 reference

28 July 2017

1 reference