(Q33718674)

English

Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay

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Europe PubMed Central

PubMed publication ID

28 July 2017

Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay (English)

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Europe PubMed Central

PubMed publication ID

28 July 2017

alternative mRNA splicing, via spliceosome

1 reference

based on heuristic

inferred from title

Mihaela Zavolan

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Nicholas J McGlincy

object named as

Nicholas J McGlincy

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Christopher W J Smith

6

object named as

Christopher W J Smith

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Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Lit-Yeen Tan

2

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Europe PubMed Central

PubMed publication ID

28 July 2017

Nicodeme Paul

3

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Europe PubMed Central

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28 July 2017

Kathryn S Lilley

5

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Europe PubMed Central

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28 July 2017

language of work or name

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publication date

14 October 2010

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Europe PubMed Central

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28 July 2017

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Europe PubMed Central

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28 July 2017

11

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Europe PubMed Central

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28 July 2017

565

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Europe PubMed Central

PubMed publication ID

28 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2164-11-565

0 references

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1 reference

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SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control

1 reference

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The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

1 reference

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

1 reference

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hnRNP A2 regulates alternative mRNA splicing of TP53INP2 to control invasive cell migration.

1 reference

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hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection

1 reference

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High resolution transcriptome maps for wild-type and nonsense-mediated decay-defective Caenorhabditis elegans

1 reference

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Global analysis of alternative splicing uncovers developmental regulation of nonsense-mediated decay in C. elegans

1 reference

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Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila

1 reference

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Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

1 reference

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28 July 2018

Nonsense-mediated mRNA decay (NMD) mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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The multiple lives of NMD factors: balancing roles in gene and genome regulation

1 reference

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Multiple and specific mRNA processing targets for the major human hnRNP proteins

1 reference

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Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

1 reference

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A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

1 reference

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Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay

1 reference

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Binding of DAZAP1 and hnRNPA1/A2 to an exonic splicing silencer in a natural BRCA1 exon 18 mutant

1 reference

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Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1

1 reference

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1 reference

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The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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Staufen1 regulates diverse classes of mammalian transcripts

1 reference

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Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors

1 reference

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Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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An alternative branch of the nonsense-mediated decay pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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The nonsense-mediated decay RNA surveillance pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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Impact of nonsense-mediated mRNA decay on the global expression profile of budding yeast

1 reference

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The canonical UPF1-dependent nonsense-mediated mRNA decay is inhibited in transcripts carrying a short open reading frame independent of sequence context

1 reference

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SPA: a probabilistic algorithm for spliced alignment

1 reference

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The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD).

1 reference

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Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, alpha (I) mRNA stability

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

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Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

1 reference

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Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

1 reference

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Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

1 reference

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Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

1 reference

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Negative feedback regulation among SR splicing factors encoded by Rbp1 and Rbp1-like in Drosophila

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Understanding alternative splicing: towards a cellular code

1 reference

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Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

1 reference

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A minor alternative transcript of the fumarylacetoacetate hydrolase gene produces a protein despite being likely subjected to nonsense-mediated mRNA decay

1 reference

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

1 reference

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Ultraconserved Elements in the Human Genome

1 reference

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1 reference

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Diversity of vertebrate splicing factor U2AF35: identification of alternatively spliced U2AF1 mRNAS.

1 reference

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Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife

1 reference

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An unappreciated role for RNA surveillance

1 reference

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Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA.

1 reference

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Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

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Splice variation in mouse full-length cDNAs identified by mapping to the mouse genome

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Increased expression of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP) in pancreatic tissue from smokers and pancreatic tumor cells

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Increased protein levels of heterogeneous nuclear ribonucleoprotein A2/B1 in fetal Down syndrome brains

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Differential expression of the early lung cancer detection marker, heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) in normal breast and neoplastic breast cancer.

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SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs

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Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

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Alternative splicing of intron 3 of the serine/arginine-rich protein 9G8 gene. Identification of flanking exonic splicing enhancers and involvement of 9G8 as a trans-acting factor

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Upstream open reading frames as regulators of mRNA translation

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28 July 2018

hnRNP complexes: composition, structure, and function

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28 July 2018

Upf1 and Upf2 proteins mediate normal yeast mRNA degradation when translation initiation is limited

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28 July 2018

smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans

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28 July 2018

Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells

1 reference

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28 July 2018

The gene encoding human splicing factor 9G8. Structure, chromosomal localization, and expression of alternatively processed transcripts

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Frameshift suppression Saccharomyces cerevisiae. II. Genetic properties of group II suppressors.

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28 July 2018

Nonsense-mediated translational repression involves exon junction complex downstream of premature translation termination codon.

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30 October 2018

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

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30 October 2018

Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival

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30 October 2018

Execution of nonsense-mediated mRNA decay: what defines a substrate?

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30 October 2018

Auto- and cross-regulation of the hnRNP L proteins by alternative splicing.

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30 October 2018

Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region

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30 October 2018

Messenger RNA regulation: to translate or to degrade

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30 October 2018

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30 October 2018

Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements

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30 October 2018

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

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30 October 2018

Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicing

1 reference

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30 October 2018

The role of SMG-1 in nonsense-mediated mRNA decay.

1 reference

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30 October 2018

A GFP-based reporter system to monitor nonsense-mediated mRNA decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Nonsense-mediated decay approaches the clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Determining a significant change in protein expression with DeCyder during a pair-wise comparison using two-dimensional difference gel electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Competing Functions Encoded in the Allergy-Associated FcϵRIβ Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

The UCSC Genome Browser Database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

RNAi-mediated PTB depletion leads to enhanced exon definition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

BLAT—The BLAST-Like Alignment Tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Untranslated regions of mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Probability-based protein identification by searching sequence databases using mass spectrometry data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Nonsense-mediated mRNA decay: target genes and functional diversification of effectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

A chemiluminescence-based reporter system to monitor nonsense-mediated mRNA decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

Downstream control of upstream open reading frames

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091714

30 October 2018

The circadian clock regulated RNA-binding protein AtGRP7 autoregulates its expression by influencing alternative splicing of its own pre-mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20946641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard

1 reference

https://pubmed.ncbi.nlm.nih.gov/20946641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of partial least squares discriminant analysis to two-dimensional difference gel studies in expression proteomics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20946641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximising sensitivity for detecting changes in protein expression: Experimental design using minimal CyDyes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20946641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2164-11-565

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-11-565

9 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

0 references

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