(Q33736505)

29 July 2017

title

Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles (English)

1 reference

29 July 2017

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computational biology

1 reference

Benjamin D Allen

1

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29 July 2017

Alex Nisthal

series ordinal

2

1 reference

29 July 2017

Stephen L Mayo

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

2 November 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

107

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29 July 2017

issue

46

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29 July 2017

page(s)

19838-19843

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X-ray vs. NMR structures as templates for computational protein design.

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Design of protein-interaction specificity gives selective bZIP-binding peptides.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Protein Design by Directed Evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Design of protein-ligand binding based on the molecular-mechanics energy model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Kemp elimination catalysts by computational enzyme design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

De novo computational design of retro-aldol enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Advances in laboratory evolution of enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

The point mutation A34F causes dimerization of GB1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

High-resolution design of a protein loop

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Progress in computational protein design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Modeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Computationally designed libraries of fluorescent proteins evaluated by preservation and diversity of function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Combinatorial methods for small-molecule placement in computational enzyme design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Dramatic performance enhancements for the FASTER optimization algorithm

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Progress in modeling of protein structures and interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Automated design of degenerate codon libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Energy functions for protein design: adjustment with protein-protein complex affinities, models for the unfolded state, and negative design of solubility and specificity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

A second-generation system for unbiased reading frame selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Protein structure prediction using Rosetta

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

A protein contortionist: core mutations of GB1 that induce dimerization and domain swapping

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Exact rotamer optimization for protein design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Combining computational and experimental screening for rapid optimization of protein properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Thoroughly sampling sequence space: large-scale protein design of structural ensembles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Core mutations switch monomeric protein GB1 into an intertwined tetramer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Energy estimation in protein design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Enzyme-like proteins by computational design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Combinatorial and computational challenges for biocatalyst design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Statistical theory for protein combinatorial libraries. Packing interactions, backbone flexibility, and the sequence variability of a main-chain structure.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Energy functions for protein design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Design, structure and stability of a hyperthermophilic protein variant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

De novo protein design: fully automated sequence selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Probing the role of packing specificity in protein design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Bayesian statistical analysis of protein side-chain rotamer preferences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

The denatured state (the other half of the folding equation) and its role in protein stability.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Two crystal structures of the B1 immunoglobulin-binding domain of streptococcal protein G and comparison with NMR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

Computational protein design promises to revolutionize protein engineering

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

Computing van der Waals energies in the context of the rotamer approximation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

Automated design of specificity in molecular recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

Computational design of a single amino acid sequence that can switch between two distinct protein folds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

Eris: an automated estimator of protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

A partition function algorithm for nucleic acid secondary structure including pseudoknots

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

An algorithm for computing nucleic acid base-pairing probabilities including pseudoknots

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

High-throughput measurement of protein stability in microtiter plates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012985107

An efficient algorithm for multistate protein design based on FASTER.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993350

30 October 2018

Identifiers

DOI

10.1073/PNAS.1012985107

1 reference

release_uirix4ohkfem5d2qp6vzgfq4n4

29 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uirix4ohkfem5d2qp6vzgfq4n4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

2993350

1 reference

29 July 2017

1 reference