(Q33747764)

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In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation

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scholarly article

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Europe PubMed Central

29 July 2017

In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation (English)

1 reference

Europe PubMed Central

29 July 2017

7

object named as

Jolene J Windle

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Europe PubMed Central

29 July 2017

author name string

Amy J Hawkins

1

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Europe PubMed Central

29 July 2017

Mark A Subler

2

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Europe PubMed Central

29 July 2017

Konstantin Akopiants

3

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Europe PubMed Central

29 July 2017

Jenny L Wiley

4

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Europe PubMed Central

29 July 2017

Shirley M Taylor

5

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Europe PubMed Central

29 July 2017

Ann C Rice

6

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29 July 2017

Kristoffer Valerie

8

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29 July 2017

Lawrence F Povirk

9

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29 July 2017

publication date

10 February 2009

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

8

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Europe PubMed Central

29 July 2017

5

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Europe PubMed Central

29 July 2017

654-663

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29 July 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2844109/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

1 reference

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GC/MS methods to quantify the 2-deoxypentos-4-ulose and 3'-phosphoglycolate pathways of 4' oxidation of 2-deoxyribose in DNA: application to DNA damage produced by gamma radiation and bleomycin

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TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo

1 reference

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21 June 2018

Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison

1 reference

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ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brain

1 reference

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TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks

1 reference

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Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts

1 reference

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Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease

1 reference

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Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes

1 reference

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SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity

1 reference

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Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

1 reference

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Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

1 reference

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APE1 is the major 3'-phosphoglycolate activity in human cell extracts

1 reference

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Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.

1 reference

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DNA single-strand break repair and spinocerebellar ataxia

1 reference

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Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

1 reference

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Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

1 reference

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21 June 2018

The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1

1 reference

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Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity

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Homogeneous preparations of 3'-phosphoglycolate-terminated oligodeoxynucleotides from bleomycin-treated DNA as verified by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

1 reference

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Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

1 reference

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Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

1 reference

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DNA end-joining catalyzed by human cell-free extracts

1 reference

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Immunohistochemical detection of DNA topoisomerase I in formalin fixed, paraffin wax embedded normal tissues and in ovarian carcinomas

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3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends

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A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

1 reference

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DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes

1 reference

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End-joining of free radical-mediated DNA double-strand breaks in vitro is blocked by the kinase inhibitor wortmannin at a step preceding removal of damaged 3' termini

1 reference

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DNA strand breaks produced by oxidative stress in mammalian cells exhibit 3'-phosphoglycolate termini.

1 reference

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Sites and structure of gamma radiation-induced DNA strand breaks

1 reference

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gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini

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Structure of bleomycin-induced DNA double-strand breaks: predominance of blunt ends and single-base 5' extensions

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Purkinje cell loss in the cerebellar flocculus in patients with ataxia with ocular motor apraxia type 1/early-onset ataxia with ocular motor apraxia and hypoalbuminemia.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19211312

12 December 2020

based on heuristic

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Development of long PCR techniques to analyze deletion mutations of the human hprt gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19211312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.DNAREP.2008.12.012

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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