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Progress toward valid transgenic mouse models for Alzheimer's disease
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Progress toward valid transgenic mouse models for Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
main subject
Alzheimer's disease
0 references
author name string
Guénette SY
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
Tanzi RE
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
publication date
1 March 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
published in
Neurobiology of Aging
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
volume
20
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
page(s)
201-211
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
cites work
Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background
1 reference
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Crossref
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7 January 2021
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Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture
1 reference
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Crossref
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7 January 2021
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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.
1 reference
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Crossref
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7 January 2021
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ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-2 macroglobulin is genetically associated with Alzheimer disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
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Rapid induction of Alzheimer A beta amyloid formation by zinc.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neuron loss in APP transgenic mice
1 reference
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Crossref
reference URL
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7 January 2021
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Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association detected between very-low-density lipoprotein receptor (VLDL-R) and late-onset Alzheimer's disease in Hong Kong Chinese.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytical processing of mutated human amyloid precursor protein in transgenic mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Association of apolipoprotein E4 with sporadic Alzheimer's disease is more pronounced in early onset type.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
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Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Polygenic determinants of Alzheimer's disease: modulation of the risk by alpha-1-antichymotrypsin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-antichymotrypsin gene polymorphism and risk for Alzheimer's disease in the Spanish population.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association between the very low density lipoprotein receptor gene and late-onset Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and clinic samples
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
M1 muscarinic agonist treatment reverses cognitive and cholinergic impairments of apolipoprotein E-deficient mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
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inferred from DOI database lookup
Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tau mutations cause frontotemporal dementias.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association between alpha 1-antichymotrypsin and familial Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mouse brain histopathology resembles early Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ApoE genotype is a risk factor in nonpresenilin early-onset Alzheimer's disease families
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant and native human beta-amyloid precursor proteins in transgenic mouse brain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic association studies between Alzheimer's disease and two polymorphisms in the low density lipoprotein receptor-related protein gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of beta-amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha 1-antichymotrypsin gene polymorphism and risk for Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association between the alpha 1-antichymotrypsin A allele and Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Implication of α1-antichymotrypsin polymorphism in familial Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease: genetic studies and transgenic models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of beta-amyloid protein deposits in brains of transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein epsilon 4 allele
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stable association of presenilin derivatives and absence of presenilin interactions with APP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha1-antichymotrypsin polymorphism in Japanese cases of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2899%2900042-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0197-4580(99)00042-1
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
PubMed ID
10537029
1 reference
stated in
Europe PubMed Central
PubMed ID
10537029
retrieved
29 July 2017
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