(Q33769079)

24936870

29 July 2017

title

Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease (English)

1 reference

29 July 2017

0 references

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

Renata Eloah de Lucena Ferretti-Rebustini

8 June 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Antonio Hugo Campos

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Dirce Carraro

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Helena Paula Brentani

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Aderbal R T Silva

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Ana Cecília Feio Santos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Jose M Farfel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Isabela Werneck Cunha

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Maria Dirlei Begnami

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Rafael M Rocha

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Carlos Alberto de Bragança Pereira

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Wilson Jacob-Filho

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

17 June 2014

1 reference

29 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

e99897

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

8 June 2020

copyright license

start time

17 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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14 July 2018

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14 July 2018

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14 July 2018

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Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex.

14 July 2018

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Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles

14 July 2018

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Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA)

14 July 2018

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The Nun study: clinically silent AD, neuronal hypertrophy, and linguistic skills in early life

14 July 2018

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14 July 2018

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Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

14 July 2018

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14 July 2018

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14 July 2018

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Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology.

14 July 2018

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Cdk5 and the non-catalytic arrest of the neuronal cell cycle

14 July 2018

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14 July 2018

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Alzheimer disease and cognitive reserve: variation of education effect with carbon 11-labeled Pittsburgh Compound B uptake

14 July 2018

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Oxidative stress hypothesis in Alzheimer's disease: a reappraisal

14 July 2018

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Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.

14 July 2018

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14 July 2018

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14 July 2018

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PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression

14 July 2018

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Defective DNA repair and neurodegenerative disease

14 July 2018

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Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment

14 July 2018

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14 July 2018

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Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons

14 July 2018

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Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry

14 July 2018

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BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

14 July 2018

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Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?

14 July 2018

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Transitions to mild cognitive impairments, dementia, and death: findings from the Nun Study.

14 July 2018

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Essential role for nuclear PTEN in maintaining chromosomal integrity

14 July 2018

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Ubiquitination regulates PTEN nuclear import and tumor suppression

14 July 2018

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Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults

14 July 2018

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Brain bank of the Brazilian aging brain study group - a milestone reached and more than 1,600 collected brains.

14 July 2018

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Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells

14 July 2018

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Cognitive reserve and Alzheimer disease.

14 July 2018

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Discriminative and predictive power of an informant report in mild cognitive impairment

14 July 2018

1 reference

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Global prevalence of dementia: a Delphi consensus study

14 July 2018

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Gene regulation and DNA damage in the ageing human brain

14 July 2018

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Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.

14 July 2018

1 reference

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TM4: a free, open-source system for microarray data management and analysis

14 July 2018

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Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

14 July 2018

Surfing the p53 network

1 reference

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E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

BRCA1 required for transcription-coupled repair of oxidative DNA damage

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Cell cycle markers in the hippocampus in Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

14 July 2018

1 reference

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Changes of p53 in the brains of patients with Alzheimer's disease.

14 July 2018

1 reference

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Mechanisms of neuronal death in Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

The Clinical Dementia Rating (CDR): current version and scoring rules

14 July 2018

1 reference

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Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

A short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): development and cross-validation.

14 July 2018

1 reference

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease

14 July 2018

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Multicenter clinicopathological correlation in dementia

14 July 2018

1 reference

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The validity of 3 clinical diagnostic criteria for Alzheimer's disease.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

14 July 2018

1 reference

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Neuropathological stageing of Alzheimer-related changes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Clinical-neuropathological correlations in Alzheimer's disease and related dementias

21 January 2018

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Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease.

21 January 2018

1 reference

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Age, neuropathology, and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Regional expression of key cell cycle proteins in brain from subjects with amnestic mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Sequential expression of cell-cycle regulators and Alzheimer's disease-related proteins in entorhinal cortex after hippocampal excitotoxic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Cyclin dependent kinase inhibitors prevent apoptosis of postmitotic mouse motoneurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Post-Mortem diagnosis of dementia by informant interview

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

"Preclinical" AD revisited: neuropathology of cognitively normal older adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Different fibrillar Abeta 1-42 concentrations induce adult hippocampal neurons to reenter various phases of the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Swedish amyloid precursor protein mutation increases cell cycle-related proteins in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Hippocampal neurons in pre-clinical Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: a summary report from the Honolulu-Asia aging study

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Increased nuclear DNA oxidation in the brain in Alzheimer's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

In situ evidence for DNA fragmentation in Huntingtonʼs disease striatum and Alzheimerʼs disease temporal lobes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061071

PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent Manner

30 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099897

Microwave-enhanced in situ end-labeling of fragmented DNA: parametric studies in relation to postmortem delay and fixation of rat and human brain

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24936870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Methods of screening for dementia: a meta-analysis of studies comparing an informant questionnaire with a brief cognitive test

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24936870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0099897

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

24936870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936870%20AND%20SRC:MED&resulttype=core&format=json