(Q33774262)

29 July 2017

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor (English)

1 reference

Malene Ringkjøbing Jensen

29 July 2017

1 reference

7

object named as

Malene Ringkjøbing Jensen

0 references

Martin Blackledge

10

object named as

Martin Blackledge

1 reference

29 July 2017

Navasona Krishnan

1

1 reference

29 July 2017

Dorothy Koveal

2

1 reference

29 July 2017

Daniel H Miller

3

1 reference

29 July 2017

Bin Xue

4

1 reference

29 July 2017

Sai Dipikaa Akshinthala

5

1 reference

29 July 2017

Jaka Kragelj

6

1 reference

29 July 2017

Carla-Maria Gauss

8

1 reference

29 July 2017

Rebecca Page

9

1 reference

29 July 2017

Senthil K Muthuswamy

11

1 reference

29 July 2017

Wolfgang Peti

12

1 reference

29 July 2017

Nicholas K Tonks

13

1 reference

29 July 2017

20 May 2014

1 reference

29 July 2017

Nature Chemical Biology

1 reference

29 July 2017

10

1 reference

29 July 2017

7

1 reference

29 July 2017

558-566

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio.1528

29 July 2017

0 references

cites work

Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Mechanisms of small-molecule binding to intrinsically disordered proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Intrinsic and acquired resistance to HER2-targeted therapies in HER2 gene-amplified breast cancer: mechanisms and clinical implications

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

PTP1B and TCPTP--nonredundant phosphatases in insulin signaling and glucose homeostasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

PTP1B expression contributes to gastric cancer progression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

PTP1B suppresses prolactin activation of Stat5 in breast cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Intrinsically disordered proteins are potential drug targets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Suppression of PTP1B in gastric cancer cells in vitro induces a change in the genome-wide expression profile and inhibits gastric cancer cell growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Acquired resistance to tyrosine kinase inhibitors during cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Protein backbone chemical shifts predicted from searching a database for torsion angle and sequence homology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

relocating job wise? A mathematical model separates quantitatively the cytostatic and cytotoxic effects of a HER2 tyrosine kinase inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Sorafenib for the treatment of advanced renal cell carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Importance of solvent accessibility and contact surfaces in modeling side-chain conformations in proteins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

The role of protein tyrosine phosphatase 1B in Ras signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

RefDB: a database of uniformly referenced protein chemical shifts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Crystal structure of human protein tyrosine phosphatase 1B

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Purification of the major protein-tyrosine-phosphatases of human placenta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

HER-2/neu amplification and overexpression in primary human breast cancer is associated with early metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Allosteric inhibition of protein tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Inside the human cancer tyrosine phosphatome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

A brake becomes an accelerator: PTP1B--a new therapeutic target for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Small molecule tools for functional interrogation of protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062594

The Noncatalytic C-terminal Segment of the T Cell Protein Tyrosine Phosphatase Regulates Activity via an Intramolecular Mechanism

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1528

Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein expression

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24845231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1528

1 reference

29 July 2017

1 reference

29 July 2017

1 reference