(Q33774895)

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Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Francis J Castellino

4

object named as

Francis J Castellino

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Angelina J Lay

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Zhong Liang

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Elliot D Rosen

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

5 May 2005

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

115

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1552-1561

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

A protein C deficiency exacerbates inflammatory and hypotensive responses in mice during polymicrobial sepsis in a cecal ligation and puncture model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

High frequency of congenital thrombophilia in women with pathological pregnancies?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Activated protein C in sepsis: emerging insights regarding its mechanism of action and clinical effectiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Activated protein C inhibits the release of macrophage inflammatory protein-1-alpha from THP-1 cells and from human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Progress in the understanding of the protein C anticoagulant pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Specificity of coagulation factor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Pre-eclampsia, the placenta and the maternal systemic inflammatory response--a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Coagulation and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Thrombophilia: implications for pregnancy outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Protein C pathway in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

New mechanisms for vascular control of inflammation mediated by natural anticoagulant proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Activated protein C in normal human pregnancy and pregnancies complicated by severe preeclampsia: a therapeutic opportunity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Recombinant human activated protein C attenuates the inflammatory response in endothelium and monocytes by modulating nuclear factor-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Regulation of trophoblast invasion: from normal implantation to pre-eclampsia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Pre-eclampsia and the inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Endothelial cell protein C receptor plays an important role in protein C activation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Activated protein C inhibits tumor necrosis factor and macrophage migration inhibitory factor production in monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Characterization of transcriptional regulatory elements in the promoter region of the murine blood coagulation factor VII gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Preparation and properties of bovine factor VIII (antihemophilic factor).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Ischemic stroke due to protein C deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Anticoagulant properties of bovine plasma protein C following activation by thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

4 July 2018

Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

30 October 2018

The thrombomodulin-protein C system is essential for the maintenance of pregnancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

30 October 2018

High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1089798

30 October 2018

Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein S is a cofactor for activated protein C neutralization of an inhibitor of plasminogen activation released from platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital severe protein C deficiency in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe pulmonary arterial hypertension caused by protein C deficiency reversible after medical treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein C deficiency as a cause of pulmonary embolism in the perioperative period

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new animal model for human preeclampsia: ultra-low-dose endotoxin infusion in pregnant rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful management of congenital protein C deficiency with recurrent pregnancy loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purpura fulminans in severe congenital protein C deficiency: monitoring of treatment with protein C concentrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide structure and characterization of the murine blood coagulation factor VII gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The successful use of protein C concentrate during pregnancy in a patient with type 1 protein C deficiency, previous thrombosis and recurrent fetal loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosomal arrangement of the murine coagulation factor VII and factor X genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of BCL-2, BAX and BAK in the Trophoblast Layer of the Term Human Placenta: a Unique Model of Apoptosis within a Syncytium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the murine coagulation factor X promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15902301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI24030

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

0 references

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