(Q33780297)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Inhibition of human immunodeficiency virus type-1 by cdk inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

ChEBI release 2020-05-28

3

1 reference

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29 January 2020

4

Fatah Kashanchi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Irene Guendel

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Emmanuel T Agbottah

series ordinal

2

1 reference

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29 January 2020

publication date

24 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

AIDS Research and Therapy

29 January 2020

published in

1 reference

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29 January 2020

volume

7

1 reference

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29 January 2020

issue

1

1 reference

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29 January 2020

page(s)

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/1742-6405-7-7

29 January 2020

exact match

0 references

cites work

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9-Aminoacridine inhibition of HIV-1 Tat dependent transcription

4 July 2018

1 reference

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Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

4 July 2018

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Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells

4 July 2018

1 reference

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Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line

4 July 2018

1 reference

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Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics

4 July 2018

1 reference

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Cdk inhibitory nucleoside analogs prevent transcription from viral genomes

4 July 2018

1 reference

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Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.

4 July 2018

1 reference

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Recent progress in the discovery and development of cyclin-dependent kinase inhibitors

4 July 2018

1 reference

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Advances on cyclin-dependent kinases (CDKs) as novel targets for antiviral drugs

4 July 2018

1 reference

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Antiviral activity of CYC202 in HIV-1-infected cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Pharmacological cyclin-dependent kinase inhibitors as HIV-1 antiviral therapeutics

4 July 2018

1 reference

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Effects of pharmacological cyclin-dependent kinase inhibitors on viral transcription and replication

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

GSK-3-selective inhibitors derived from Tyrian purple indirubins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Cyclin-dependent kinases as cellular targets for antiviral drugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Pharmacological inhibitors of cyclin-dependent kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy

4 July 2018

1 reference

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GSK3 takes centre stage more than 20 years after its discovery

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Missing links in GSK3 regulation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Loss of G(1)/S checkpoint in human immunodeficiency virus type 1-infected cells is associated with a lack of cyclin-dependent kinase inhibitor p21/Waf1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

The tumor suppressor protein p53 strongly alters human immunodeficiency virus type 1 replication

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Regulation of human immunodeficiency virus infection: implications for pathogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

HIV-1 tat trans-activation requires the loop sequence within tar.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

RNA recognition by Tat-derived peptides: interaction in the major groove?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

RNA binding assays for Tat-derived peptides: implications for specificity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar

4 July 2018

1 reference

Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis

21 January 2018

1 reference

The decline in paediatric malaria admissions on the coast of Kenya

21 January 2018

1 reference

Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya

21 January 2018

1 reference

Cost-effectiveness study of three antimalarial drug combinations in Tanzania

21 January 2018

1 reference

Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study

21 January 2018

1 reference

Access to antimalarial therapy: accurate diagnosis is essential to achieving long term goals.

21 January 2018

1 reference

Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator

21 January 2018

1 reference

Molecular diagnostic and surveillance tools for global malaria control

21 January 2018

1 reference

Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy.

21 January 2018

1 reference

Making malaria testing relevant: beyond test purchase

21 January 2018

1 reference

Ensuring quality and access for malaria diagnosis: how can it be achieved?

21 January 2018

1 reference

Evidence behind the WHO guidelines: hospital care for children: what is the precision of rapid diagnostic tests for malaria?

21 January 2018

1 reference

Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya

21 January 2018

1 reference

Overdiagnosis of malaria in hospitalized patients in Namibia

21 January 2018

1 reference

Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial

21 January 2018

1 reference

Guidelines and mindlines: why do clinical staff over-diagnose malaria in Tanzania? A qualitative study.

21 January 2018

1 reference

The importance of context in malaria diagnosis and treatment decisions - a quantitative analysis of observed clinical encounters in Tanzania.

21 January 2018

1 reference

Malaria overdiagnosis: is patient pressure the problem?

21 January 2018

1 reference

Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Phase I clinical and pharmacokinetic study of flavopiridol in children with refractory solid tumors: a Children's Oncology Group Study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Lithium ameliorates HIV-gp120-mediated neurotoxicity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

A model of the G1 phase of the cell cycle incorporating cyclin E/cdk2 complex and retinoblastoma protein.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852372

Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

30 October 2018

1 reference

12 December 2020

Direct evidence that HIV-1 Tat stimulates RNA polymerase II carboxyl-terminal domain hyperphosphorylation during transcriptional elongation

1 reference

12 December 2020

R-roscovitine (CYC202) alleviates renal cell proliferation in nephritis without aggravating podocyte injury

1 reference

12 December 2020

Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

1 reference

12 December 2020

Identifiers

DOI

10.2217/THY.09.94

1 reference

PubMed ID

20334651

29 July 2017

10.1186/1742-6405-7-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference