(Q33780879)

29 July 2017

1 reference

title

Homeostatic disinhibition in the aging brain and Alzheimer's disease (English)

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29 July 2017

0 references

1 reference

3

Mark P Mattson

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29 July 2017

Marc Gleichmann

1

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29 July 2017

Vivian W Chow

series ordinal

2

1 reference

29 July 2017

language of work or name

1 reference

1 January 2011

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Journal of Alzheimer's Disease

29 July 2017

published in

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29 July 2017

volume

24

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29 July 2017

issue

1

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29 July 2017

page(s)

15-24

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Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks

29 July 2017

cites work

1 reference

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4 July 2018

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Amyloid-modifying therapies for Alzheimer's disease: therapeutic progress and its implications

4 July 2018

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Controversy: Noninvasive and invasive cortical stimulation show efficacy in treating stroke patients

4 July 2018

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Neuronal calcium homeostasis and dysregulation

4 July 2018

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Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

4 July 2018

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An epigenetic hypothesis of aging-related cognitive dysfunction

4 July 2018

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Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline

4 July 2018

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The Alzheimer's Disease Neuroimaging Initiative: Annual change in biomarkers and clinical outcomes

4 July 2018

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The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core

4 July 2018

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The Alzheimer's disease neuroimaging initiative: progress report and future plans

4 July 2018

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Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning

4 July 2018

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Alzheimer's disease: strategies for disease modification

4 July 2018

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Putting brain training to the test

4 July 2018

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Alzheimer's prevention initiative: a proposal to evaluate presymptomatic treatments as quickly as possible

4 July 2018

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Cerebrospinal fluid biomarkers of Alzheimer's disease

4 July 2018

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Neural mechanisms of ageing and cognitive decline

4 July 2018

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Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons

4 July 2018

1 reference

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Dementia incidence continues to increase with age in the oldest old: the 90+ study

4 July 2018

1 reference

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Functional alterations in memory networks in early Alzheimer's disease

4 July 2018

1 reference

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Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy

4 July 2018

1 reference

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Molecular network analysis suggests aberrant CREB-mediated gene regulation in the Alzheimer disease hippocampus

4 July 2018

1 reference

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Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin?

4 July 2018

1 reference

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Consensus: "Can tDCS and TMS enhance motor learning and memory formation?"

4 July 2018

1 reference

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Alzheimer's disease amyloid beta-protein and synaptic function

4 July 2018

1 reference

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Does Alzheimer's disease begin in the brainstem?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Amyloid deposition is associated with impaired default network function in older persons without dementia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Epileptic seizures in AD patients

4 July 2018

1 reference

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Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans

4 July 2018

1 reference

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Resting GABA concentration predicts peak gamma frequency and fMRI amplitude in response to visual stimulation in humans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

4 July 2018

1 reference

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Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

4 July 2018

1 reference

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Can training in a real-time strategy video game attenuate cognitive decline in older adults?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Glutamate and neurotrophic factors in neuronal plasticity and disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

The adaptive brain: aging and neurocognitive scaffolding

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

The pathology of APP transgenic mice: a model of Alzheimer's disease or simply overexpression of APP?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Evolution of the aging brain transcriptome and synaptic regulation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Potential adaptive function for altered long-term potentiation mechanisms in aging hippocampus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Prevalence of dementia in the United States: the aging, demographics, and memory study.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Somatostatin in the dentate gyrus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Alterations of hippocampal and prefrontal GABAergic interneurons in an animal model of psychosis induced by NMDA receptor antagonism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Visual hallucinations and agitation in Alzheimer's disease due to memantine: report of three cases.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Human EEG gamma oscillations in neuropsychiatric disorders.

4 July 2018

1 reference

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Aging and gene expression in the primate brain

4 July 2018

1 reference

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Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

4 July 2018

1 reference

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Associations of cortical astrogliosis with cognitive performance and dementia status

4 July 2018

1 reference

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SGS742: the first GABA(B) receptor antagonist in clinical trials

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Gene regulation and DNA damage in the ageing human brain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Healthy aging and dementia: findings from the Nun Study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

First one in, last one out: the role of gabaergic transmission in generation and degeneration

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Microglia in degenerative neurological disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Activity-dependent changes in GAD and preprotachykinin mRNAs in visual cortex of adult monkeys.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Staging of Alzheimer's disease-related neurofibrillary changes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Activity-dependent regulation of GABA expression in the visual cortex of adult monkeys

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Baseline GABA concentration and fMRI response

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Perspective on the Alzheimer's disease neuroimaging initiative: progress report and future plans.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Amplification of small electric fields by neurons; implications for spike timing.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Delusions and hallucinations in dementia with Lewy bodies: worsening with memantine.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Dementia and Alzheimer disease incidence: a prospective cohort study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4543386

30 October 2018

Identifiers

DOI

10.3233/JAD-2010-101674

1 reference

29 July 2017

1 reference

29 July 2017

1 reference