(Q48100081)

8 February 2018

http://europepmc.org/abstract/MED/20685980

title

Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies (English)

1 reference

8 February 2018

http://europepmc.org/abstract/MED/20685980

1 reference

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

author name string

Heinz Hillen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Stefan Barghorn

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Andreas Striebinger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Boris Labkovsky

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Reinhold Müller

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Volker Nimmrich

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Marc W Nolte

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Claudia Perez-Cruz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Ingrid van der Auwera

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Fred van Leuven

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Marcel van Gaalen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Hans Schoemaker

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

James P Sullivan

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

Ulrich Ebert

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 August 2010

1 reference

8 February 2018

http://europepmc.org/abstract/MED/20685980

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

issue

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

page(s)

10369-10379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

15 May 2020

cites work

1 reference

12 December 2020

The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging

1 reference

12 December 2020

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

12 December 2020

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

1 reference

12 December 2020

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Cerebral hemorrhage after passive anti-Abeta immunotherapy

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

12 December 2020

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

1 reference

12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

12 December 2020

Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease.

1 reference

12 December 2020

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

1 reference

12 December 2020

Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

1 reference

12 December 2020

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

12 December 2020

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

1 reference

12 December 2020

beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons.

1 reference

12 December 2020

Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach

1 reference

12 December 2020

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

1 reference

12 December 2020

Monoclonal antibodies that target pathological assemblies of Abeta

1 reference

12 December 2020

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

12 December 2020

A beta oligomers - a decade of discovery

1 reference

12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

1 reference

12 December 2020

Antibody capture of soluble Abeta does not reduce cortical Abeta amyloidosis in the PDAPP mouse

1 reference

12 December 2020

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

1 reference

12 December 2020

Abeta-globulomers are formed independently of the fibril pathway

1 reference

12 December 2020

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

12 December 2020

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

1 reference

12 December 2020

Collagen VI protects neurons against Abeta toxicity

1 reference

12 December 2020

Structural characterization of a soluble amyloid beta-peptide oligomer.

1 reference

12 December 2020

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

1 reference

12 December 2020

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

10.1523/JNEUROSCI.5721-09.2010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634649&resulttype=core&format=json

15 May 2020

1 reference