(Q33784044)

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Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Alzheimer's disease

0 references

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

dementia with Lewy bodies

1 reference

based on heuristic

inferred from title

Dennis W. Dickson

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Pamela J McLean

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Ashley R Winslow

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Liya Zhu

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kathryn L Post

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Oksana Berezovska

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

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publication date

24 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

137

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Pt 7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1958-1970

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

α-Synuclein is localized to mitochondria-associated ER membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Oxidative stress response elicited by mitochondrial dysfunction: implication in the pathophysiology of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Stress proteins in aging and life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Solid-state ¹³C NMR reveals annealing of raft-like membranes containing cholesterol by the intrinsically disordered protein α-Synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Oxidative stress and mitochondrial protein quality control in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

α-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Familial aggregation of dementia with Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Autophagy impairment stimulates PS1 expression and gamma-secretase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

The first N-terminal amino acids of alpha-synuclein are essential for alpha-helical structure formation in vitro and membrane binding in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Formation of toxic oligomeric alpha-synuclein species in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Lewy body pathology in familial Alzheimer disease: evidence for disease- and mutation-specific pathologic phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Novel presenilin 1 mutation (S170F) causing Alzheimer disease with Lewy bodies in the third decade of life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Familial occurrence of dementia with Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Familial dementia with Lewy bodies with an atypical clinical presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Familial parkinsonism, dementia, and Lewy body disease: study of family G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

4 July 2018

Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Familial diffuse Lewy body disease, eye movement abnormalities, and distribution of pathology.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Lipid rafts mediate the synaptic localization of alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Neuropathology of dementia in a large cohort of patients with Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

A mutant PSEN1 causes dementia with Lewy bodies and variant Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

DLB and PDD: a role for mutations in dementia and Parkinson disease genes?

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Identification of neuronal plasma membrane microdomains that colocalize beta-amyloid and presenilin: implications for beta-amyloid precursor protein processing

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Autosomal dominant Lewy body parkinsonism in a four-generation family

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

30 October 2018

Familial dementia with Lewy bodies (DLB).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

30 October 2018

Enrichment of presenilin 1 peptides in neuronal large dense-core and somatodendritic clathrin-coated vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065023

30 October 2018

Dementia with Lewy bodies

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWU119

21 January 2018

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production

1 reference

https://pubmed.ncbi.nlm.nih.gov/24860142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly sensitive protein-protein interaction assay based on Gaussia luciferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24860142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/BRAIN/AWU119

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

release_thetzwrhtvh5bpbebtfccik5ai

1 reference

https://api.fatcat.wiki/v0/release/thetzwrhtvh5bpbebtfccik5ai

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24860142%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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