(Q33790424)

29 July 2017

title

RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events (English)

1 reference

29 July 2017

0 references

17

Bruce Beutler

1 reference

29 July 2017

Alice Mayer

8

0 references

Bénédicte Manoury

Bénédicte Manoury

16

0 references

Alison Simmons

Alison Simmons

19

0 references

Owen M Siggs

Owen Siggs

9

0 references

Roman Fischer

Roman Fischer

11

0 references

Adrian V. S. Hill

15

Adrian V S Hill

1 reference

29 July 2017

Alasdair Leslie

2

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author name string

Elif Colak

1

1 reference

29 July 2017

Kieran Zausmer

3

1 reference

29 July 2017

Elham Khatamzas

4

1 reference

29 July 2017

Andriy V Kubarenko

5

1 reference

29 July 2017

Tica Pichulik

6

1 reference

29 July 2017

Sascha N Klimosch

7

1 reference

29 July 2017

Andreas Hector

10

1 reference

29 July 2017

Benedikt Klesser

12

1 reference

29 July 2017

Anna Rautanen

13

1 reference

29 July 2017

Martin Frank

14

1 reference

29 July 2017

Dominik Hartl

18

1 reference

29 July 2017

Alexander N R Weber

20

1 reference

29 July 2017

language of work or name

English

0 references

publication date

9 May 2014

1 reference

29 July 2017

published in

Journal of Immunology

1 reference

29 July 2017

volume

192

1 reference

29 July 2017

issue

12

1 reference

29 July 2017

page(s)

5963-5973

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4066583/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4066583

based on heuristic

inferred from PubMed Central ID database lookup

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4 July 2018

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Cleaved/associated TLR3 represents the primary form of the signaling receptor

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

4 July 2018

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Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding

4 July 2018

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A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding

4 July 2018

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4 July 2018

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Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

4 July 2018

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Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly

4 July 2018

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Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

4 July 2018

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A Naturally Occurring Variant in Human TLR9, P99L, Is Associated with Loss of CpG Oligonucleotide Responsiveness

4 July 2018

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Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

4 July 2018

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4 July 2018

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4 July 2018

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TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

4 July 2018

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4 July 2018

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Clinical considerations in developing dendritic cell vaccine based immunotherapy protocols in cancer

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Pyogenic bacterial infections in humans with MyD88 deficiency

4 July 2018

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

4 July 2018

1 reference

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The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation

4 July 2018

1 reference

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4 July 2018

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

4 July 2018

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4 July 2018

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Oligodeoxynucleotides differentially modulate activation of TLR7 and TLR8 by imidazoquinolines

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Toll-like receptors as molecular switches

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Conserved features in the extracellular domain of human toll-like receptor 8 are essential for pH-dependent signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

TLR ligands induce synergistic interferon-β and interferon-λ1 gene expression in human monocyte-derived dendritic cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066583

A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24813206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1303058

1 reference

29 July 2017

1 reference

29 July 2017

1 reference