(Q33791851)

English

Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modification

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modification (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Lactobacillus leichmannii

object named as

Lactobacillus leichmannii

1 reference

based on heuristic

inferred from title

2

object named as

Joanne Stubbe

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Gregory J S Lohman

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

1 February 2010

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1404-1417

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Treatment of advanced pancreatic cancer: from gemcitabine single agent to combinations and targeted therapy.

1 reference

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4 July 2018

Pharmacogenomics of gemcitabine in non-small-cell lung cancer and other solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Efficacy of systemic therapy in advanced pancreatic carcinoma

1 reference

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Second-line strategies for metastatic renal cell carcinoma: classics and novel approaches

1 reference

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Update on chemotherapy for advanced bladder cancer

1 reference

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Combination of chemotherapy without platinum compounds in the treatment of advanced non-small cell lung cancer: a systematic review of phase III trials

1 reference

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4 July 2018

Combined modality therapy of gemcitabine and radiation

1 reference

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4 July 2018

Antitumor activity of sugar-modified cytosine nucleosides

1 reference

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4 July 2018

Current approaches to novel therapeutics in pancreatic cancer

1 reference

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4 July 2018

Lung cancer: a review

1 reference

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4 July 2018

The structure of Escherichia coli cytosine deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Gemcitabine in hematologic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

The role of gemcitabine alone and in combination in the treatment of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Gemcitabine: a cytidine analogue active against solid tumors

1 reference

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4 July 2018

Cloning, sequencing, and expression of the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Gemcitabine: metabolism, mechanisms of action, and self-potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Inactivation of the Lactobacillus leichmannii ribonucleoside triphosphate reductase by 2'-chloro-2'-deoxyuridine 5'-triphosphate: stoichiometry of inactivation, site of inactivation, and mechanism of the protein chromophore formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Direct cloning of the trxB gene that encodes thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Evidence for two different classes of redox-active cysteines in ribonucleotide reductase of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855214

4 July 2018

Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine

1 reference

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4 July 2018

Enzyme Ribonucleotide Reductase: Unraveling an Enigmatic Paradigm of Enzyme Inhibition by Furanone Derivatives

1 reference

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30 October 2018

A rapid assay for CDP reductase activity in mammalian cell extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification and purification of plasmid-encoded thioredoxin from Escherichia coli K12

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location of the redox-active thiols of ribonucleotide reductase: sequence similarity between the Escherichia coli and Lactobacillus leichmannii enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coenzyme B12-dependent ribonucleotide reductase: evidence for the participation of five cysteine residues in ribonucleotide reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of high salt concentrations on the regulation of the substrate specificity of human recombinant deoxycytidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemcitabine 5'-triphosphate is a stoichiometric mechanism-based inhibitor of Lactobacillus leichmannii ribonucleoside triphosphate reductase: evidence for thiyl radical-mediated nucleotide radical formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the catalysis of carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: evidence for concerted carbon-cobalt bond homolysis and thiyl radical formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamic and kinetic studies on carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: the importance of entropy in catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20088569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI902132U

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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