(Q33796294)

29 July 2017

title

The N terminus of monoamine transporters is a lever required for the action of amphetamines (English)

1 reference

29 July 2017

12

1 reference

29 July 2017

Barbara Zdrazil

3

0 references

Sonja Sucic

Sonja Sucic

1

0 references

Harald H Sitte

Harald H Sitte

14

0 references

Ulrik Gether

Ulrik Gether

10

0 references

Michael Freissmuth

Michael Freissmuth

13

0 references

Amy Hauck Newman

11

Amy H Newman

1 reference

29 July 2017

7

Oliver Kudlacek

1 reference

29 July 2017

4

René Weissensteiner

1 reference

29 July 2017

Stefan Dallinger

2

1 reference

29 July 2017

Trine N Jørgensen

5

1 reference

29 July 2017

Marion Holy

6

1 reference

29 July 2017

Stefan Seidel

8

1 reference

29 July 2017

Joo Hwan Cha

9

1 reference

29 July 2017

language of work or name

English

0 references

publication date

29 January 2010

1 reference

Journal of Biological Chemistry

29 July 2017

published in

1 reference

29 July 2017

volume

285

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29 July 2017

issue

14

1 reference

29 July 2017

page(s)

10924-10938

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2856298/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs

4 July 2018

1 reference

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Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP

4 July 2018

1 reference

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A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

LeuT: a prokaryotic stepping stone on the way to a eukaryotic neurotransmitter transporter structure

4 July 2018

1 reference

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Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a prerequisite for correct axonal targeting.

4 July 2018

1 reference

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Mechanism for alternating access in neurotransmitter transporters

4 July 2018

1 reference

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Anomalous dopamine release associated with a human dopamine transporter coding variant

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

An intracellular interaction network regulates conformational transitions in the dopamine transporter.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate compartment is specified by a C-terminal motif

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

4 July 2018

1 reference

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Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Regulation of the dopamine transporter by phosphorylation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Currents in neurotransmitter transporters

4 July 2018

1 reference

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Zn2+ modulation of neurotransmitter transporters.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

TCDB: the Transporter Classification Database for membrane transport protein analyses and information

4 July 2018

1 reference

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Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The effect of phosphorylation on amphetamine-mediated outward transport

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Oligomerization of Dopamine Transporters Visualized in Living Cells by Fluorescence Resonance Energy Transfer Microscopy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The role of zinc ions in reverse transport mediated by monoamine transporters.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Regulation of the serotonin transporter by interacting proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The FLAG peptide, a versatile fusion tag for the purification of recombinant proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Modulation of serotonin transporter activity by a protein kinase C activator and an inhibitor of type 1 and 2A serine/threonine phosphatases.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

VMD: visual molecular dynamics

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Norepinephrine transporters have channel modes of conduction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Simple Allosteric Model for Membrane Pumps

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

The interleukin-2 receptor.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Dopamine transporters are phosphorylated on N-terminal serines in rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Zinc potentiates an uncoupled anion conductance associated with the dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Glycine transporter dimers: evidence for occurrence in the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Conducting states of a mammalian serotonin transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Ibogaine, a noncompetitive inhibitor of serotonin transport, acts by stabilizing the cytoplasm-facing state of the transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Delineation of an endogenous zinc-binding site in the human dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Production, purification, and characterization of recombinant 2', 5'-oligoadenylate synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Intracellular domains of a rat brain GABA transporter that govern transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.083154

Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Ion binding and permeation at the GABA transporter GAT1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856298

Förster distances between green fluorescent protein pairs.

30 October 2018

1 reference

12 December 2020

Ion-coupled neurotransmitter transport: thermodynamic vs. kinetic determinations of stoichiometry

1 reference

12 December 2020

Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action

1 reference

12 December 2020

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.083154

1 reference

29 July 2017

1 reference

29 July 2017

1 reference