(Q33814783)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

3

1 reference

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29 January 2020

author name string

Stephen P Persaud

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

David L Donermeyer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

David M Kranz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Paul M Allen

5

1 reference

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29 January 2020

publication date

23 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

47

1 reference

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29 January 2020

issue

9

1 reference

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29 January 2020

page(s)

1793-1801

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists

29 January 2020

cites work

1 reference

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How a single T cell receptor recognizes both self and foreign MHC

28 July 2018

1 reference

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Display, engineering, and applications of antigen-specific T cell receptors

28 July 2018

1 reference

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How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?

28 July 2018

1 reference

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Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor

28 July 2018

1 reference

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Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

28 July 2018

1 reference

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The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy.

28 July 2018

1 reference

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Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide

28 July 2018

1 reference

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How TCRs bind MHCs, peptides, and coreceptors

28 July 2018

1 reference

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Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope

28 July 2018

1 reference

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Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

T cell cross-reactivity and conformational changes during TCR engagement

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Targeting virus entry and membrane fusion through specific peptide/MHC complexes using a high-affinity T-cell receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Molecular interactions mediating T cell antigen recognition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

TCRs with high affinity for foreign pMHC show self-reactivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

A comparative analysis of the immunological evolution of antibody 28B4

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Structural and functional consequences of altering a peptide MHC anchor residue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Selective activation of the calcium signaling pathway by altered peptide ligands

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Essential flexibility in the T-cell recognition of antigen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Formation of functional peptide complexes of class II major histocompatibility complex proteins from subunits produced in Escherichia coli

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Kinetic proofreading in T-cell receptor signal transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Positive selection of thymocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Thermodynamics of structural stability and cooperative folding behavior in proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Noncognate interaction with MHC class II molecules is essential for maintenance of T cell metabolism to establish optimal memory CD4 T cell function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction

30 October 2018

1 reference

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Molecular flexibility can influence the stimulatory ability of receptor-ligand interactions at cell-cell junctions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Energetics of the cooperative assembly of cell division protein FtsZ and the nucleotide hydrolysis switch

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Structural characterisation and functional significance of transient protein-protein interactions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Impairment of immunological memory in the absence of MHC despite survival of memory T cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

High affinity T cell receptors from yeast display libraries block T cell activation by superantigens.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Ligand recognition by alpha beta T cell receptors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Kinetic discrimination in T-cell activation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Structural energetics of peptide recognition: Angiotensin II/antibody binding

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860700

Distinct molecular mechanisms account for the specificity of two different T-cell receptors

30 October 2018

1 reference

12 December 2020

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

1 reference

12 December 2020

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

12 December 2020

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

1 reference

12 December 2020

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1 reference

12 December 2020

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

1 reference

12 December 2020

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

12 December 2020

Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand

1 reference

12 December 2020

10.1016/J.MOLIMM.2010.02.013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334923%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

20334923

1 reference