(Q33816341)

29 July 2017

title

VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis (English)

1 reference

29 July 2017

1

Tiffany N Seagroves

1 reference

29 July 2017

Danielle L Peacock

2

1 reference

29 July 2017

Debbie Liao

3

1 reference

29 July 2017

Luciana P Schwab

4

1 reference

29 July 2017

Robin Krueger

5

1 reference

29 July 2017

Charles R Handorf

6

1 reference

29 July 2017

Volker H Haase

7

1 reference

29 July 2017

Randall S Johnson

8

1 reference

29 July 2017

language of work or name

English

0 references

publication date

9 April 2010

1 reference

The American Journal of Pathology

29 July 2017

published in

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29 July 2017

volume

176

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29 July 2017

issue

5

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29 July 2017

page(s)

2269-2282

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Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer

29 July 2017

cites work

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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p66Shc/Notch-3 interplay controls self-renewal and hypoxia survival in human stem/progenitor cells of the mammary gland expanded in vitro as mammospheres

4 July 2018

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4 July 2018

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Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.

4 July 2018

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Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells

4 July 2018

1 reference

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pVHL function is essential for endothelial extracellular matrix deposition.

4 July 2018

1 reference

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Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor

4 July 2018

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Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors

4 July 2018

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Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

4 July 2018

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Generation of a functional mammary gland from a single stem cell

4 July 2018

1 reference

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Purification and unique properties of mammary epithelial stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Stem cells in the etiology and treatment of cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Hypoxia requires notch signaling to maintain the undifferentiated cell state

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Hypoxia activates the cyclin D1 promoter via the Jak2/STAT5b pathway in breast cancer cells

4 July 2018

1 reference

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The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting.

4 July 2018

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Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

von Hippel-Lindau tumor suppressor: not only HIF's executioner

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts

4 July 2018

1 reference

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Von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

von Hippel-Lindau disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Mammary physiology and milk secretion

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

The Arias-Stella reaction: facts and fancies four decades after

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Transcriptional regulation of vascular endothelial growth factor expression in epithelial and stromal cells during mouse mammary gland development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

C/EBPbeta (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Regulation of milk protein gene expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

C/EBPbeta, but not C/EBPalpha, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Cre-mediated gene deletion in the mammary gland

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Chemotherapy and cancer stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Cancer stem cells in radiation resistance.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Hypoxia-Inducible Factor-1 Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861092

Expression of the von Hippel-Lindau gene protein in breast cancer tissue

30 October 2018

1 reference

12 December 2020

Von Hippel-Lindau disease

1 reference

12 December 2020

Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues

1 reference

12 December 2020

Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression

1 reference

12 December 2020

Overexpression of hypoxia-inducible factor HIF-1alpha predicts early relapse in breast cancer: retrospective study in a series of 745 patients

1 reference

12 December 2020

Von Hippel-Lindau gene alterations in sporadic benign and malignant pheochromocytomas

1 reference

12 December 2020

TheVon Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas

1 reference

12 December 2020

Mutations of the VHL tumour suppressor gene in renal carcinoma

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NG0594-85

Identifiers

DOI

10.2353/AJPATH.2010.090310

1 reference

29 July 2017

1 reference

29 July 2017

1 reference