(Q33824444)

29 July 2017

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title

Blood-based biomarkers of Alzheimer's disease: challenging but feasible (English)

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29 July 2017

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Simon Lovestone

2

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Madhav Thambisetty

series ordinal

1

object named as

Madhav Thambisetty

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29 July 2017

publication date

1 February 2010

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29 July 2017

published in

Biomarkers in Medicine

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29 July 2017

volume

4

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29 July 2017

issue

1

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29 July 2017

page(s)

65-79

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Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

29 July 2017

cites work

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Role of oxidative stress in the progression of Alzheimer's disease

4 July 2018

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MicroRNA expression in Alzheimer blood mononuclear cells

4 July 2018

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4 July 2018

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Emerging risk factors for coronary heart disease: a summary of systematic reviews conducted for the U.S. Preventive Services Task Force

4 July 2018

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Association of C-reactive protein with mild cognitive impairment

4 July 2018

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Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-old

4 July 2018

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Multidimensional protein identification technology for clinical proteomic analysis

4 July 2018

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Exosomes: proteomic insights and diagnostic potential

4 July 2018

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Plasma biomarkers for mild cognitive impairment and Alzheimer's disease.

4 July 2018

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Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients

4 July 2018

1 reference

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Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease

4 July 2018

1 reference

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Glycogen-synthase kinase-3beta is decreased in peripheral blood mononuclear cells of patients with mild cognitive impairment

4 July 2018

1 reference

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Affinity prefractionation for MS-based plasma proteomics

4 July 2018

1 reference

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Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Detection of microRNA expression in human peripheral blood microvesicles

4 July 2018

1 reference

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Target identification for CNS diseases by transcriptional profiling.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Identification of a 5-protein biomarker molecular signature for predicting Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

List of drugs in development for neurodegenerative diseases. Update June 2008.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Gene expression study on peripheral blood identifies progranulin mutations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Hyperhomocysteinemia and Alzheimer's disease: A systematic review

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Cholesterol as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Mining the plasma proteome for cancer biomarkers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Plasma biomarkers of Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Oxysterols, cholesterol homeostasis, and Alzheimer disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Plasma/serum proteomics: pre-analytical issues.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Inflammatory markers and the risk of Alzheimer disease: the Framingham Study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Risk factors for dementia: data from the Conselice study of brain aging

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Plasma proteome analysis: 2D gels and chips.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Proteome-based plasma biomarkers for Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Predictors of conversion to dementia of probable Alzheimer type in patients with mild cognitive impairment

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

The Alzheimer's disease neuroimaging initiative

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Homocysteine and folate as risk factors for dementia and Alzheimer disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Mining biomarkers in human sera using proteomic tools

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Cross‐Linked Fibrin Degradation Products (D‐Dimer), Plasma Cytokines, and Cognitive Decline in Community‐Dwelling Elderly Persons

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Identification of oxidized plasma proteins in Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

The dynamic range of protein expression: a challenge for proteomic research

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Amyloid beta protein in plasma from patients with sporadic Alzheimer's disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Identification of fast and slow decliners in Alzheimer disease: a different approach

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Alzheimer's disease: the amyloid cascade hypothesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications.

4 July 2018

1 reference

Gene expression as peripheral biomarkers for sporadic Alzheimer's disease.

21 January 2018

1 reference

Differential RNA expression between schizophrenic patients and controls of the dystrobrevin binding protein 1 and neuregulin 1 genes in immortalized lymphocytes

21 January 2018

1 reference

Gene expression changes in peripheral mononuclear cells from schizophrenic patients treated with a combination of antipsychotic with fluvoxamine

21 January 2018

1 reference

Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia.

21 January 2018

1 reference

Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels.

21 January 2018

1 reference

The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease.

21 January 2018

1 reference

Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.

21 January 2018

1 reference

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.

21 January 2018

1 reference

Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study.

21 January 2018

1 reference

Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease.

21 January 2018

1 reference

Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-beta protein transport across the blood-brain barrier in Alzheimer's disease.

21 January 2018

1 reference

Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

21 January 2018

1 reference

Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease.

21 January 2018

1 reference

Plasma levels of beta-amyloid (1-42) in Alzheimer's disease and mild cognitive impairment.

21 January 2018

1 reference

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

21 January 2018

1 reference

Elevated serum homocysteine level is not associated with serum C-reactive protein in patients with probable Alzheimer's disease.

21 January 2018

1 reference

Inflammatory proteins in plasma and the risk of dementia: the rotterdam study

21 January 2018

1 reference

Altered cytokine and acute phase response protein levels in the blood of children with Downs syndrome: relationship with dementia of Alzheimer's type

21 January 2018

1 reference

Is there a relationship between high C-reactive protein (CRP) levels and dementia?

21 January 2018

1 reference

Plasma C-reactive protein is related to cognitive deterioration and dementia in patients with mild cognitive impairment.

21 January 2018

1 reference

Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease

21 January 2018

1 reference

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

21 January 2018

1 reference

Identifying early markers of Alzheimer's disease using quantitative multiplex proteomic immunoassay panels.

21 January 2018

1 reference

Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease

21 January 2018

1 reference

'How far' vs 'how fast' in Alzheimer's disease. The question revisited.

21 January 2018

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Serum biomarkers for Alzheimer's disease: proteomic discovery.

21 January 2018

1 reference

Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium-derived factor: Two novel biomarkers of Alzheimer's disease in human plasma.

21 January 2018

1 reference

Biomarkers in brain disease. Preface.

21 January 2018

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Serum cholesterol changes after midlife and late-life cognition: twenty-one-year follow-up study.

21 January 2018

1 reference

Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients

21 January 2018

1 reference

Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimer's disease patients and their potential as biomarkers.

21 January 2018

1 reference

Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia.

21 January 2018

1 reference

Plasma fibrinogen is associated with cognitive decline and risk for dementia in patients with mild cognitive impairment.

21 January 2018

1 reference

Plasma homocysteine levels and risk of Alzheimer disease

21 January 2018

1 reference

In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Biological variations and genetic reference values for apolipoprotein E serum concentrations: results from the STANISLAS cohort study.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863057

Association of plasma amyloid with risk of dementia: The prospective Three-City Study

29 October 2018

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Apolipoprotein E serum concentration and polymorphism in six European countries: the ApoEurope Project

21 January 2018

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Apolipoprotein E polymorphism and serum concentration in Alzheimer's disease in nine European centres: the ApoEurope study. ApoEurope group

21 January 2018

1 reference

12 December 2020

Coagulation and fibrinolysis markers and risk of dementia. The Dutch Vascular Factors in Dementia Study

1 reference

12 December 2020

The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone

1 reference

12 December 2020

Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity

1 reference

12 December 2020

Progression from MCI to AD: Predictive value of CSF Aβ42 is modified by APOE genotype

1 reference

12 December 2020

AddNeuroMed--the European collaboration for the discovery of novel biomarkers for Alzheimer's disease

1 reference

12 December 2020

Identifiers

DOI

10.2217/BMM.09.84

1 reference

29 July 2017

1 reference

29 July 2017

1 reference