(Q33837238)

English

Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases

scientific article

Combination therapy with Coenzyme Q10and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Huntington's disease

0 references

0 references

Parkinson's disease

1 reference

based on heuristic

inferred from title

Robert J Ferrante

6

object named as

Robert J Ferrante

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

7

object named as

M Flint Beal

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Lichuan Yang

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Noel Y Calingasan

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Elizabeth J Wille

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Kerry Cormier

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Karen Smith

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

28 March 2009

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Journal of Neurochemistry

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

109

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1427-1439

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

The creatine kinase/creatine connection to Alzheimer's disease: CK-inactivation, APP-CK complexes and focal creatine deposits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Translating therapies for Huntington's disease from genetic animal models to clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Experimental therapeutics in transgenic mouse models of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Metabolism and function of coenzyme Q.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Superoxide activates mitochondrial uncoupling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

On the mechanisms of neuroprotection by creatine and phosphocreatine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Biochemical, physiological and medical aspects of ubiquinone function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

4 July 2018

Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2009.06074.X

21 January 2018

Creatine supplementation in Huntington's disease: a placebo-controlled pilot trial

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2009.06074.X

21 January 2018

Experimental schistosomal hepatitis: protective effect of coenzyme-Q10 against the state of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Protective effect of creatine supplementation and estrogen replacement on cardiac reserve function and antioxidant reservation against oxidative stress in exercise-trained ovariectomized hamsters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Improved reperfusion and neuroprotection by creatine in a mouse model of stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Neurochemical correlates of differential neuroprotection by long-term dietary creatine supplementation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Antioxidant treatment of patients with Friedreich ataxia: four-year follow-up

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Additive neuroprotective effects of creatine and a cyclooxygenase 2 inhibitor against dopamine depletion in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Protective effects of oral creatine supplementation on spinal cord injury in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Rapid, fluorimetric-liquid chromatographic determination of malondialdehyde in biological samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Creatine and cyclocreatine attenuate MPTP neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866530

29 October 2018

Paraquat induces oxidative stress and neuronal cell death; neuroprotection by water-soluble Coenzyme Q10

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NIH announces phase III clinical trial of creatine for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective Effect of the Energy Precursor Creatine Against Toxicity of Glutamate and β-Amyloid in Rat Hippocampal Neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of creatine monohydrate retards progression of motor neuron disease in the wobbler mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulometric electrochemical detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary supplement creatine protects against traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of creatine administration against NMDA and malonate toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid peroxidation and changes in the ubiquinone content and the respiratory chain enzymes of submitochondrial particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relations between tocopherol depletion and coenzyme Q during lipid peroxidation in rat liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19476553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1471-4159.2009.06074.X

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

0 references

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