(Q33847584)

29 July 2017

title

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM (English)

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29 July 2017

Timothy B Niewold

9

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Amit K. Maiti

series ordinal

1

object named as

Maiti AK

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Kim-Howard X

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Motghare P

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Pradhan V

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Chua KH

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Sun C

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Arango-Guerrero MT

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Ghosh K

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Harley JB

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Anaya JM

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Looger LL

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Nath SK

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29 July 2017

language of work or name

English

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publication date

7 March 2014

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29 July 2017

published in

Human Molecular Genetics

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29 July 2017

volume

23

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29 July 2017

issue

15

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29 July 2017

page(s)

4161-4176

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Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils

29 July 2017

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Human lupus serum induces neutrophil-mediated organ damage in mice that is enabled by Mac-1 deficiency

5 July 2018

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The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

5 July 2018

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Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases

5 July 2018

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A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis

5 July 2018

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ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry

5 July 2018

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5 July 2018

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Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression

5 July 2018

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5 July 2018

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CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082363

Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082363

The role of nuclear factor-kappaB in the development of autoimmune diseases: a link between genes and environment.

5 July 2018

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Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-alpha regulation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

5 July 2018

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Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells.

5 July 2018

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The life and death of DNA-PK.

5 July 2018

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5 July 2018

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5 July 2018

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Transcription factors in the pathogenesis of autoimmunity

5 July 2018

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Hypercoagulability as a cause of stroke in adults

5 July 2018

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Bcl11a is essential for normal lymphoid development

5 July 2018

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Transient transfection of the human myeloid cell line Mono Mac 6 using electroporation

5 July 2018

1 reference

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Conformational regulation of integrin structure and function

5 July 2018

1 reference

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A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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21 January 2018

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Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

1 reference

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5 July 2018

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Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors.

5 July 2018

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Regulation of chaperone gene expression by heat shock transcription factor in Saccharomyces cerevisiae: importance in normal cell growth, stress resistance, and longevity.

21 January 2018

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Heat shock protein 90beta: a novel mediator of vitamin D action

21 January 2018

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Analysis of nucleic acid binding by a recombinant translin-trax complex

21 January 2018

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Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model

21 January 2018

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Thrombotic disease in systemic lupus erythematosus is associated with a maintained systemic platelet activation

21 January 2018

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Erythrocyte aggregation in patients with systemic lupus erythematosus.

21 January 2018

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Isolation and characterization of the receptor on human neutrophils that mediates cellular adherence

29 October 2018

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Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands

29 October 2018

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29 October 2018

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A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

29 October 2018

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Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis

21 January 2018

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Vitronectin colocalizes with Ig deposits and C9 neoantigen in discoid lupus erythematosus and dermatitis herpetiformis, but not in bullous pemphigoid

21 January 2018

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12 December 2020

Inflammation in patients with lupus anticoagulant and implications for thrombosis

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12 December 2020

Epistatic effect of plasminogen activator inhibitor 1 and beta-fibrinogen genes on risk of glomerular microthrombosis in lupus nephritis: interaction with environmental/clinical factors

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Monocytes and macrophages in focal glomerulosclerosis in Zucker rats

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12 December 2020

Elevated levels of the 90 kD heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90 beta gene

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12 December 2020

Autoantibodies in systemic lupus erythematosus

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12 December 2020

Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells

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12 December 2020

Polymorphisms and phyletic relationships of the Paisa community from Antioquia (Colombia)

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12 December 2020

The regulation of heat shock proteins and their role in systemic lupus erythematosus

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12 December 2020

Increased Fibrin Polymerization Rate in Patients with Primary Antiphospholipid Syndrome and Systemic Lupus Erythematosus

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12 December 2020

Identification of a heat shock-responsive cis-acting DNA sequence and its transcriptional regulator: Their roles in the expression of the Spirulina-desD gene in response to heat stress

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12 December 2020

Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome

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12 December 2020

ITGAM Arg77His is associated with disease susceptibility, arthritis, and renal symptoms in systemic lupus erythematosus patients from a sample of the Polish population

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDU106

1 reference

29 July 2017

1 reference

29 July 2017

1 reference