(Q33847602)

29 July 2017

title

Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies (English)

1 reference

29 July 2017

1 reference

Elena V Wisely

1

1 reference

29 July 2017

Yang K Xiang

series ordinal

2

1 reference

29 July 2017

Salvatore Oddo

series ordinal

3

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29 July 2017

publication date

13 March 2014

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29 July 2017

published in

Human Molecular Genetics

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29 July 2017

volume

23

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29 July 2017

issue

15

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29 July 2017

page(s)

4024-4034

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Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice

29 July 2017

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5 July 2018

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Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Protein kinase A phosphorylation of tau-serine 214 reorganizes microtubules and disrupts the endothelial cell barrier

5 July 2018

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Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

5 July 2018

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Adverse stress, hippocampal networks, and Alzheimer's disease

5 July 2018

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Effects of cardiovascular medications on rate of functional decline in Alzheimer disease.

5 July 2018

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Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

5 July 2018

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Adrenergic pharmacology and cognition: focus on the prefrontal cortex

5 July 2018

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

5 July 2018

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Emerging concepts and therapeutic implications of beta-adrenergic receptor subtype signaling

5 July 2018

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GSK3 inhibitors: development and therapeutic potential

5 July 2018

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Astrocytic beta2-adrenergic receptors and multiple sclerosis

5 July 2018

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

5 July 2018

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A mechanism converting psychosocial stress into mononuclear cell activation

5 July 2018

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Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

5 July 2018

1 reference

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Chronic restraint stress promotes lymphocyte apoptosis by modulating CD95 expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

Targeted disruption of the beta2 adrenergic receptor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease

5 July 2018

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Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients.

5 July 2018

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Mechanism of activation of protein kinase B by insulin and IGF-1

5 July 2018

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Involvement of the amygdala in memory storage: Interaction with other brain systems

5 July 2018

1 reference

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Implications of genetic variability of human beta 2-adrenergic receptor structure

5 July 2018

1 reference

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Phosphorylation of recombinant tau by cAMP-dependent protein kinase. Identification of phosphorylation sites and effect on microtubule assembly.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

Differential effect of phosphorylation and substrate modulation on tau's ability to promote microtubule growth and nucleation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

Polymorphisms at the beta2-adrenergic receptor gene influence Alzheimer's disease susceptibility.

5 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Antihypertensive medication use and incident Alzheimer disease: the Cache County Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Noradrenergic mechanisms in neurodegenerative diseases: a theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Glucocorticoids exacerbate cognitive deficits in TDP-25 transgenic mice via a glutathione-mediated mechanism: implications for aging, stress and TDP-43 proteinopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Activation of β2-adrenoceptor enhances synaptic potentiation and behavioral memory via cAMP-PKA signaling in the medial prefrontal cortex of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU116

Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

Hierarchical phosphorylation of recombinant tau by the paired-helical filament-associated protein kinase is dependent on cyclic AMP-dependent protein kinase.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082366

Increased alpha 2- and beta 2-adrenergic receptors in cerebral microvessels in Alzheimer disease

29 October 2018

1 reference

12 December 2020

A proline-rich region of the third intracellular loop imparts phenotypic beta 1-versus beta 2-adrenergic receptor coupling and sequestration

1 reference

12 December 2020

Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau

1 reference

12 December 2020

Noninvasive in vivo assessment of muscle impairment in the mdx mouse model--a comparison of two common wire hanging methods with two different results

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDU116

1 reference

29 July 2017

1 reference

29 July 2017

1 reference