(Q33873538)

29 July 2017

title

Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency virus-1 Tat-mediated activation of microglial cells (English)

1 reference

29 July 2017

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2

Sanjay B Maggirwar

1 reference

29 July 2017

Michelle Kiebala

1

1 reference

29 July 2017

language of work or name

English

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publication date

8 April 2011

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29 July 2017

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29 July 2017

volume

6

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29 July 2017

issue

4

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29 July 2017

page(s)

e18633

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

8 April 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3072977/fullTextXML

inferred from PubMed Central ID database lookup

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Missing pieces in the NF-kappaB puzzle

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

1 reference

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Ibudilast suppresses TNFalpha production by glial cells functioning mainly as type III phosphodiesterase inhibitor in the CNS.

5 July 2018

1 reference

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Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia

5 July 2018

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5 July 2018

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Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT

5 July 2018

1 reference

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HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

5 July 2018

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Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-alpha

5 July 2018

1 reference

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Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.

5 July 2018

1 reference

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High-dose pentoxifylline in patients with AIDS: inhibition of tumor necrosis factor production. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group

5 July 2018

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A role for phosphorylation and degradation in the control of NF-κB activity

5 July 2018

1 reference

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Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

5 July 2018

1 reference

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

5 July 2018

1 reference

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Early penetration of the blood-brain-barrier by HIV.

5 July 2018

1 reference

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Cellular uptake of the tat protein from human immunodeficiency virus

5 July 2018

1 reference

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Persistence of neuropsychologic deficits despite long-term highly active antiretroviral therapy in patients with HIV-related neurocognitive impairment: prevalence and risk factors

5 July 2018

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Correlation of in vivo neuroimaging abnormalities with postmortem human immunodeficiency virus encephalitis and dendritic loss

21 January 2018

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Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center

21 January 2018

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Inflammatory changes and breakdown of microvascular integrity in early human immunodeficiency virus dementia

21 January 2018

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Neuronal density in the superior frontal and temporal gyri does not correlate with the degree of human immunodeficiency virus-associated dementia

21 January 2018

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Expression of chemokines by human fetal microglia after treatment with the human immunodeficiency virus type 1 protein Tat.

21 January 2018

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A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment.

21 January 2018

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Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study.

21 January 2018

1 reference

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Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia.

21 January 2018

1 reference

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Immunomodulatory properties of pentoxifylline are mediated via adenosine-dependent pathways

21 January 2018

1 reference

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Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism

21 January 2018

1 reference

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Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms

21 January 2018

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Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage

21 January 2018

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Pentoxifylline attenuates leukoreduced stored blood-induced neutrophil activation through inhibition of mitogen-activated protein kinases

21 January 2018

1 reference

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Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon

21 January 2018

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Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons

21 January 2018

1 reference

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Mechanism of NF-kappaB inactivation induced by survival signal withdrawal in cerebellar granule neurons

21 January 2018

1 reference

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HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-kappaB pathways.

21 January 2018

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Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia

21 January 2018

1 reference

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LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression

21 January 2018

1 reference

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Elevated cyclic AMP inhibits NF-kappaB-mediated transcription in human monocytic cells and endothelial cells.

21 January 2018

1 reference

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Phosphodiesterase inhibition decreases nuclear factor-kappaB activation and shifts the cytokine response toward anti-inflammatory activity in acute endotoxemia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072977

Effects of phosphodiesterase inhibitors on cytokine production by microglia

29 October 2018

1 reference

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Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center.

29 October 2018

1 reference

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HIV-TAT protein upregulates expression of multidrug resistance protein 1 in the blood-brain barrier

29 October 2018

1 reference

12 December 2020

Pentoxifylline decreases up-regulated nuclear factor kappa B activation and cytokine production in the rat retina following transient ischemia

1 reference

12 December 2020

Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism

1 reference

12 December 2020

The maximal tolerable intravenous dosage of pentoxifylline in AIDS patients does not inhibit lipopolysaccharide-stimulated tumor necrosis factor alpha production

1 reference

12 December 2020

Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis

1 reference

12 December 2020

Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites

1 reference

12 December 2020

Gene expression of monocyte chemoattractant protein-1 in human monocytes is regulated by cell density through protein tyrosine kinase and protein kinase C

1 reference

12 December 2020

Pentoxifylline in vivo down-regulates the release of IL-1 beta, IL-6, IL-8 and tumour necrosis factor-alpha by human peripheral blood mononuclear cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0018633

Identifiers

DOI

1 reference

release_ks3dzilkvjggnod5xmthnewroq

29 July 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ks3dzilkvjggnod5xmthnewroq

24 November 2022

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PMC publication ID

3072977

1 reference

29 July 2017

1 reference