(Q33879398)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429511%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery (English)

1 reference

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1 February 2020

0 references

1 reference

3

1 reference

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1 February 2020

Frederick S Buckner

8

1 reference

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1 February 2020

9

Michael H Gelb

1 reference

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1 February 2020

7

Christophe L M J Verlinde

1 reference

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Naveen Kumar Chennamaneni

1 February 2020

4

object named as

Naveen Kumar Chennamaneni

1 reference

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1 February 2020

James Alexander Kraus

1

object named as

James M Kraus

1 reference

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1 February 2020

2

Hari Babu Tatipaka

1 reference

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1 February 2020

6

Jenifer Arif

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429511%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Mandana Karimi

5

1 reference

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1 February 2020

language of work or name

English

0 references

publication date

1 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429511%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

1 February 2020

published in

1 reference

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1 February 2020

volume

53

1 reference

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1 February 2020

issue

10

1 reference

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1 February 2020

page(s)

3887-3898

1 reference

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Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease.

1 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Rational modification of a candidate cancer drug for use against Chagas disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Farnesyl protein transferase inhibitor ZARNESTRA R115777 - history of a discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Parasitology. Drugs to combat tropical protozoan parasites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Current status of clinical trials of farnesyltransferase inhibitors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Access to essential drugs in poor countries: a lost battle?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877169

5 July 2018

Identifiers

DOI

10.1021/JM9013136

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429511%20AND%20SRC:MED&resulttype=core&format=json

release_c4nifd2tlzcp3pvfbpqz75wmie

1 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c4nifd2tlzcp3pvfbpqz75wmie

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429511%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

20429511

1 reference