(Q33888941)

PubMed publication ID

29 July 2017

2 references

20 August 2020

High affinity, developability and functional size: the holy grail of combinatorial antibody library generation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

1 reference

protein primary structure

1 reference

20 August 2020

Dirk Ponsel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

Julia Neugebauer

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

Kathrin Ladetzki-Baehs

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

Kathrin Tissot

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

3 May 2011

2 references

PubMed publication ID

29 July 2017

20 August 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

20 August 2020

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

page(s)

3675-3700

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

Creative Commons Attribution

13 May 2020

copyright license

1 reference

20 August 2020

0 references

Harnessing phage and ribosome display for antibody optimisation

1 reference

12 December 2020

'Camelising' human antibody fragments: NMR studies on VH domains.

1 reference

12 December 2020

Unique single‐domain antigen binding fragments derived from naturally occurring camel heavy‐chain antibodies

1 reference

12 December 2020

Tyrosine plays a dominant functional role in the paratope of a synthetic antibody derived from a four amino acid code

1 reference

12 December 2020

In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity

1 reference

12 December 2020

Strategies for analysis of the glycosylation of proteins: current status and future perspectives

1 reference

12 December 2020

Selection of phage antibodies by binding affinity. Mimicking affinity maturation

1 reference

12 December 2020

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

1 reference

12 December 2020

Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis

1 reference

12 December 2020

Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3.

1 reference

12 December 2020

Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains

1 reference

12 December 2020

Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning

1 reference

12 December 2020

Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library

1 reference

12 December 2020

A new helper phage and phagemid vector system improves viral display of antibody Fab fragments and avoids propagation of insert-less virions

1 reference

12 December 2020

Phage display technology: clinical applications and recent innovations

1 reference

12 December 2020

Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds

1 reference

12 December 2020

Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection

1 reference

12 December 2020

By-passing immunization. Human antibodies from V-gene libraries displayed on phage

1 reference

12 December 2020

Antibodies from phage antibody libraries

1 reference

12 December 2020

The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

1 reference

12 December 2020

Design of synthetic antibody libraries

1 reference

12 December 2020

Therapeutic antibody fragments with prolonged in vivo half-lives

1 reference

12 December 2020

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold

1 reference

12 December 2020

High-throughput generation and engineering of recombinant human antibodies

1 reference

12 December 2020

Synthetic antibodies from a four-amino-acid code: a dominant role for tyrosine in antigen recognition

1 reference

12 December 2020

In vitro selection from protein and peptide libraries

1 reference

12 December 2020

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

1 reference

12 December 2020

Exploiting recombination in single bacteria to make large phage antibody libraries

1 reference

12 December 2020

Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions

1 reference

12 December 2020

Antibody fragments from a 'single pot' phage display library as immunochemical reagents

1 reference

12 December 2020

Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology

1 reference

12 December 2020

Development trends for human monoclonal antibody therapeutics

1 reference

12 December 2020

Neutralizing human Fab fragments against measles virus recovered by phage display

1 reference

12 December 2020

Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

1 reference

12 December 2020

Human anti-self antibodies with high specificity from phage display libraries.

1 reference

12 December 2020

An in vitro polysome display system for identifying ligands from very large peptide libraries

1 reference

12 December 2020

Fast selection of antibodies without antigen purification: adaptation of the protein fragment complementation assay to select antigen-antibody pairs.

1 reference

12 December 2020

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

1 reference

12 December 2020

Engineering antibody heavy chain CDR3 to create a phage display Fab library rich in antibodies that bind charged carbohydrates

1 reference

12 December 2020

In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology

1 reference

12 December 2020

A helper phage to improve single-chain antibody presentation in phage display

1 reference

12 December 2020

In vitro DNA recombination by L-Shuffling during ribosome display affinity maturation of an anti-Fas antibody increases the population of improved variants

1 reference

12 December 2020

Protein affinity maturation in vivo using E. coli mutator cells

1 reference

12 December 2020

Isolation of human monoclonal antibodies by mammalian cell display

1 reference

12 December 2020

Single-domain antibody fragments with high conformational stability

1 reference

12 December 2020

Overview of antibody phage-display technology and its applications

1 reference

12 December 2020

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

1 reference

12 December 2020

Isolation of high affinity human antibodies directly from large synthetic repertoires.

1 reference

12 December 2020

General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold

1 reference

12 December 2020

A vector for the removal of deletion mutants from antibody libraries

1 reference

12 December 2020

Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain

1 reference

12 December 2020

A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein

1 reference

12 December 2020

The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries

1 reference

12 December 2020

Yeast surface display for screening combinatorial polypeptide libraries

1 reference

12 December 2020

Affinity maturation by phage display

1 reference

12 December 2020

In vitro affinity maturation of human GM-CSF antibodies by targeted CDR-diversification

1 reference

12 December 2020

By-passing immunization: building high affinity human antibodies by chain shuffling

1 reference

12 December 2020

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

1 reference

12 December 2020

Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens

1 reference

12 December 2020

Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries

1 reference

12 December 2020

Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation rates

1 reference

12 December 2020

DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution

1 reference

12 December 2020

Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain

1 reference

12 December 2020

Molecular recognition by a binary code

1 reference

12 December 2020

Sequence statistics reliably predict stabilizing mutations in a protein domain

1 reference

12 December 2020

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

1 reference

12 December 2020

Biophysical Properties of Camelid VHHDomains Compared to Those of Human VH3 Domains†

1 reference

12 December 2020

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

1 reference

12 December 2020

Aggregation-resistant domain antibodies selected on phage by heat denaturation

1 reference

12 December 2020

Selection of antibodies for intracellular function using a two-hybrid in vivo system

1 reference

12 December 2020

Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody

1 reference

12 December 2020

Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library

1 reference

12 December 2020

Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

1 reference

12 December 2020

Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination

1 reference

12 December 2020

Construction of large naïve Fab libraries.

1 reference

12 December 2020

1 reference

12 December 2020

Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.

1 reference

12 December 2020

Human combinatorial antibody libraries to hepatitis B surface antigen

1 reference

12 December 2020

Novel helper phage design: intergenic region affects the assembly of bacteriophages and the size of antibody libraries

1 reference

12 December 2020

Have we overestimated the benefit of human(ized) antibodies?

1 reference

12 December 2020

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

1 reference

12 December 2020

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1 reference

12 December 2020

n-CoDeR concept: unique types of antibodies for diagnostic use and therapy

1 reference

12 December 2020

Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires

1 reference

12 December 2020

Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability

1 reference

12 December 2020

Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity

1 reference

12 December 2020

Yeast mating for combinatorial Fab library generation and surface display

1 reference

12 December 2020

Filamentous phage infection-mediated gene expression: construction and propagation of the gIII deletion mutant helper phage R408d3.

1 reference

12 December 2020

Single domain camel antibodies: current status.

1 reference

12 December 2020

Affinity improvement of single antibody VH domains: residues in all three hypervariable regions affect antigen binding

1 reference

12 December 2020

Optimal design features of camelized human single-domain antibody libraries

1 reference

12 December 2020

Naturally occurring antibodies devoid of light chains

1 reference

12 December 2020

Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions

1 reference

12 December 2020

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

1 reference

12 December 2020

By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

1 reference

12 December 2020

An antibody single-domain phage display library of a native heavy chain variable region: isolation of functional single-domain VH molecules with a unique interface.

1 reference

12 December 2020

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

1 reference

12 December 2020

Antigen-independent selection of intracellular stable antibody frameworks

1 reference

12 December 2020

Selection for improved protein stability by phage display.

1 reference

12 December 2020

Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

1 reference

12 December 2020

Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.

1 reference

12 December 2020

Antibody VH domains as small recognition units

1 reference

12 December 2020

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

1 reference

12 December 2020

An improved helper phage system for efficient isolation of specific antibody molecules in phage display

1 reference

12 December 2020

Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability

1 reference

12 December 2020

In vitro selection and evolution of functional proteins by using ribosome display

1 reference

12 December 2020

Single domain antibodies: comparison of camel VH and camelised human VH domains

1 reference

12 December 2020

10.3390/MOLECULES16053675

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6263270&resulttype=core&format=json

13 May 2020

PubMed publication ID

21540796

1 reference