(Q33896439)

29 July 2017

title

Human and mouse granzyme M display divergent and species-specific substrate specificities (English)

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29 July 2017

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Kris Gevaert

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Kim Plasman

5

object named as

Kim Plasman

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29 July 2017

Stefanie A H de Poot

1

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29 July 2017

Marijn Westgeest

2

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29 July 2017

Daniel R Hostetter

3

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29 July 2017

Kimberly Demeyer

6

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29 July 2017

Roel Broekhuizen

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29 July 2017

Charles S Craik

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29 July 2017

Niels Bovenschen

10

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29 July 2017

language of work or name

English

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publication date

1 August 2011

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29 July 2017

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29 July 2017

volume

437

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29 July 2017

issue

3

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29 July 2017

page(s)

431-442

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Lymphocyte-mediated cytotoxicity.

29 July 2017

cites work

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A role for granzyme M in TLR4-driven inflammation and endotoxicosis.

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Human and mouse granzyme A induce a proinflammatory cytokine response.

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Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells

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Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B

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The cytotoxic protease granzyme M is expressed by lymphocytes of both the innate and adaptive immune system

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Granzyme M mediates a novel form of perforin-dependent cell death

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Characterizing the anti-tumor function of adoptively transferred NK cells in vivo

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Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing

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Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells

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Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis.

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Functional analysis of granzyme M and its role in immunity to infection

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Altered substrate specificity of drug-resistant human immunodeficiency virus type 1 protease

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Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

21 January 2018

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Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A.

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Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M

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On the size of the active site in proteases. I. Papain

21 January 2018

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Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs

21 January 2018

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Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

21 January 2018

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21 January 2018

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Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

21 January 2018

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Human and murine granzyme B exhibit divergent substrate preferences

21 January 2018

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The major human and mouse granzymes are structurally and functionally divergent

21 January 2018

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Probing the efficiency of proteolytic events by positional proteomics

21 January 2018

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The nucleolar phosphoprotein B23 interacts with hepatitis delta antigens and modulates the hepatitis delta virus RNA replication.

21 January 2018

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Identification of nucleophosmin/B23, an acidic nucleolar protein, as a stimulatory factor for in vitro replication of adenovirus DNA complexed with viral basic core proteins.

21 January 2018

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Unique conformation of cancer autoantigen B23 in hepatoma: a mechanism for specificity in the autoimmune response

21 January 2018

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SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity

21 January 2018

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21 January 2018

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Improved visualization of protein consensus sequences by iceLogo

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20110210

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29 July 2017

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