(Q33897006)

English

Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3).

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3). (English)

1 reference

Europe PubMed Central

29 July 2017

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904966%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Haijun Chen

1

1 reference

Europe PubMed Central

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7 June 2020

Zhengduo Yang

2

1 reference

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7 June 2020

Chunyong Ding

3

1 reference

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7 June 2020

Ailian Xiong

4

1 reference

Europe PubMed Central

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7 June 2020

Christopher Wild

5

1 reference

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7 June 2020

Lili Wang

6

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7 June 2020

Na Ye

7

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7 June 2020

Guoshuai Cai

8

1 reference

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7 June 2020

Rudolfo M Flores

9

1 reference

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7 June 2020

Ye Ding

10

1 reference

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7 June 2020

Jia Zhou

12

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7 June 2020

publication date

22 May 2014

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29 July 2017

European Journal of Medicinal Chemistry

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7 June 2020

82

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7 June 2020

195-203

1 reference

Europe PubMed Central

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7 June 2020

Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

A combined bioinformatics and chemoinformatics approach for developing asymmetric bivalent AMPA receptor positive allosteric modulators as neuroprotective agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Signal transducer and activator of transcription 3 inhibitors: a patent review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

STATs in cancer inflammation and immunity: a leading role for STAT3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

STAT3 as a target for inducing apoptosis in solid and hematological tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Small molecule inhibitors of Stat3 signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

The STATs of cancer--new molecular targets come of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Stat proteins and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

STAT proteins: novel molecular targets for cancer drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

STATs in oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

The role of STATs in transcriptional control and their impact on cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Three-dimensional structure of the Stat3beta homodimer bound to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

STATs and gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

5 July 2018

Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096847

29 October 2018

Validating Stat3 in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24904966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting STAT3 in cancer: how successful are we?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24904966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Finding the sweet spot: the role of nature and nurture in medicinal chemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/24904966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EJMECH.2014.05.049

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904966%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904966%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904966%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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