Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q33899139)
Watch
English
The Jak-STAT pathway
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The Jak-STAT pathway
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
author name string
K Imada
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
W J Leonard
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
publication date
1 January 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
published in
Molecular Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
volume
37
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
page(s)
1-11
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
issue
1-2
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
cites work
Defective IL-2-mediated IL-2 receptor alpha chain expression in Stat3-deficient T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functionally distinct isoforms of STAT5 are generated by protein processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat3 as an oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific inhibition of Stat3 signal transduction by PIAS3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of the mammalian Stat gene family in mouse chromosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak-STAT signaling induced by the v-abl oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STATs and gene regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new protein containing an SH2 domain that inhibits JAK kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Twenty proteins containing a C-terminal SOCS box form five structural classes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The state of the STATs: recent developments in the study of signal transduction to the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine receptor signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STATs: signal transducers and activators of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The significance of tetramerization in promoter recruitment by Stat5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in dictyostelium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors keep cytokines in check
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STATs and cytokine specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jaks and STATs: biological implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Stat1-mediated gene activation by PIAS1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat5a is mandatory for adult mammary gland development and lactogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat1 depends on transcriptional synergy with Sp1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SOCS3 is essential in the regulation of fetal liver erythropoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of novel CIS family genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperation of the transcriptional coactivators CBP and p300 with Stat6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the STAT6 SH2 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of a new STAT-induced STAT inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective lymphoid development in mice lacking Jak3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak2 is essential for signaling through a variety of cytokine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse interleukin-2 receptor alpha gene expression. Interleukin-1 and interleukin-2 control transcription via distinct cis-acting elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of cytokine-inducible inhibitors of signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interactions between Stat5 and the glucocorticoid receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of Stat6 in IL-4 signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein tyrosine kinase in the interferon alpha/beta signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the amino-terminal protein interaction domain of STAT-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Naturally occurring dominant negative variants of Stat5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a Stat gene that functions in Drosophila development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of serine phosphorylation for formation of STAT-promoter complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT3 acts as a co-activator of glucocorticoid receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2800%2900018-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0161-5890(00)00018-3
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
PubMed ID
10781830
1 reference
stated in
Europe PubMed Central
PubMed ID
10781830
retrieved
29 July 2017
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit