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Prodrug-activating systems in suicide gene therapy.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Prodrug-activating systems in suicide gene therapy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
main subject
suicide
0 references
gene therapy
0 references
author
Caroline J Springer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
I Niculescu-Duvaz
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
language of work or name
English
0 references
publication date
1 May 2000
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
105
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
1161-1167
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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Self-immolative anthracycline prodrugs for suicide gene therapy
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Self-immolative nitrogen mustard prodrugs for suicide gene therapy.
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Superior cytotoxicity with ganciclovir compared with acyclovir and 1-beta-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing cells: a novel paradigm for cell killing.
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5 July 2018
The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme-prodrug therapies
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5 July 2018
Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo
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5 July 2018
Gene-directed enzyme prodrug therapy: quantitative bystander cytotoxicity and DNA damage induced by CB1954 in cells expressing bacterial nitroreductase
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Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene
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Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy
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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
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Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts
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Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions
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29 October 2018
Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells
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29 October 2018
Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452
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29 October 2018
Bystander tumoricidal effect and gap junctional communication in lung cancer cell lines.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452
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29 October 2018
A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452
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29 October 2018
Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival.
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452
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29 October 2018
Gene-Directed Enzyme Prodrug Therapy
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PubMed Central
reference URL
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29 October 2018
Gene-directed enzyme prodrug therapy with a mustard prodrug/carboxypeptidase G2 combination
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452
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29 October 2018
In vivo analysis of the 'bystander effect': a cytokine cascade
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10791987
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10791987
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Concomitant expression of E. coli cytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10791987
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI10001
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PMC publication ID
315452
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
10791987
1 reference
stated in
Europe PubMed Central
PMC publication ID
315452
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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