(Q33907086)

29 July 2017

title

The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1. (English)

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29 July 2017

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4

Agnes Görlach

1 reference

29 July 2017

Isabel Diebold

1

1 reference

29 July 2017

Andreas Petry

series ordinal

2

1 reference

29 July 2017

John Hess

series ordinal

3

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29 July 2017

publication date

28 April 2010

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Molecular Biology of the Cell

29 July 2017

published in

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29 July 2017

volume

21

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29 July 2017

issue

12

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29 July 2017

page(s)

2087-2096

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The hypoxia-inducible factor-2alpha is stabilized by oxidative stress involving NOX4.

29 July 2017

cites work

1 reference

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NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3.

5 July 2018

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5 July 2018

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5 July 2018

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Oxygen sensing in hypoxic pulmonary vasoconstriction: using new tools to answer an age-old question

5 July 2018

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5 July 2018

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ROS signaling in systemic and cellular responses to chronic intermittent hypoxia

5 July 2018

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Regulation of Nox and Duox enzymatic activity and expression

5 July 2018

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Cytosolic NAD(P)H regulation of redox signaling and vascular oxygen sensing

5 July 2018

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NOX5 variants are functionally active in endothelial cells

5 July 2018

1 reference

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Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

5 July 2018

1 reference

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Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms

5 July 2018

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NOX2 and NOX4 mediate proliferative response in endothelial cells.

5 July 2018

1 reference

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Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells

5 July 2018

1 reference

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Acute oxygen-sensing mechanisms

5 July 2018

1 reference

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Hypoxic pulmonary vasoconstriction: mechanisms and controversies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Integration of oxygen signaling at the consensus HRE.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.

5 July 2018

1 reference

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The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells

5 July 2018

1 reference

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Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells

5 July 2018

1 reference

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Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells

5 July 2018

1 reference

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Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

The neutrophil NADPH oxidase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

NAD(P)H oxidase: role in cardiovascular biology and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Superoxide in the pulmonary circulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Signal transduction by reactive oxygen species in non-phagocytic cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

5 July 2018

NADPH oxidase: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Reactive oxygen species and vascular signal transduction mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Hypoxia upregulates the synthesis of TGF-beta 1 by human dermal fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

NAD(P)H oxidases regulate HIF-2alpha protein expression.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Chronic hypoxia activates a local angiotensin-generating system in rat carotid body.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Reactive oxygen species alter contractile properties of pulmonary arterial smooth muscle.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883952

Rac-1 promotes pulmonary artery smooth muscle cell proliferation by upregulation of plasminogen activator inhibitor-1: role of NFkappaB-dependent hypoxia-inducible factor-1alpha transcription

29 October 2018

1 reference

12 December 2020

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

1 reference

12 December 2020

Effect of chronic hypoxia on contents of urotensin II and its functional receptors in rat myocardium

1 reference

12 December 2020

Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E09-12-1003

1 reference

29 July 2017

1 reference

29 July 2017

1 reference