(Q33911309)

30 July 2017

Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice (English)

1 reference

30 July 2017

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1 reference

1 reference

1 reference

Lisa F Ventrella-Lucente

1

1 reference

30 July 2017

Archana Unnikrishnan

2

1 reference

30 July 2017

Amanda B Pilling

3

1 reference

30 July 2017

Hiral V Patel

4

1 reference

30 July 2017

Deepa Kushwaha

5

1 reference

30 July 2017

Alan A Dombkowski

6

1 reference

30 July 2017

Eva M Schmelz

7

1 reference

30 July 2017

Diane C Cabelof

8

1 reference

30 July 2017

Ahmad R Heydari

9

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30 July 2017

language of work or name

English

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publication date

19 April 2010

1 reference

Journal of Biological Chemistry

30 July 2017

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30 July 2017

285

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30 July 2017

25

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30 July 2017

19246-19258

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PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

A novel function of adenomatous polyposis coli (APC) in regulating DNA repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Effects of dietary folate on DNA strand breaks within mutation-prone exons of the p53 gene in rat colon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Aberrant crypt foci: A review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Folate depletion impairs DNA excision repair in the colon of the rat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Role of aberrant crypt foci in understanding the pathogenesis of colon cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Nutritional folate-deficiency in Chinese hamster ovary cells. Chromosomal abnormalities associated with perturbations in nucleic acid precursors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: putative preneoplastic lesions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Increased uracil misincorporation in lymphocytes from folate-deficient rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.069807

Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Deficiency in DNA polymerase beta provokes replication-dependent apoptosis via DNA breakage, Bcl-2 decline and caspase-3/9 activation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885203

Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats

29 October 2018

1 reference

12 December 2020

'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status

1 reference

12 December 2020

Nutritional folate deficiency augments the in vivo mutagenic and lymphocytotoxic activities of alkylating agents

1 reference

12 December 2020

The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents

1 reference

12 December 2020

The effect of dietary folic acid deficiency on the cytotoxic and mutagenic responses to methyl methanesulfonate in wild-type and in 3-methyladenine DNA glycosylase-deficient Aag null mice

1 reference

12 December 2020

Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes

1 reference

12 December 2020

Folate Deficiency In Vitro Induces Uracil Misincorporation and DNA Hypomethylation and Inhibits DNA Excision Repair in Immortalized Normal Human Colon Epithelial Cells

1 reference

12 December 2020

Impact of folate deficiency on DNA stability

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.069807

1 reference

30 July 2017

1 reference

30 July 2017

1 reference