(Q33915185)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Christopher R. Vakoc

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

J Shi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

E Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

A Rappaport

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

M Taylor

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

C Johns

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

S W Lowe

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

language of work or name

English

0 references

publication date

2 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

page(s)

930-938

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2012.110

27 January 2020

exact match

0 references

cites work

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CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis

5 July 2018

1 reference

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The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states

5 July 2018

1 reference

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An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

5 July 2018

1 reference

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

5 July 2018

1 reference

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Clinical effect of point mutations in myelodysplastic syndromes

5 July 2018

1 reference

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Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

5 July 2018

1 reference

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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

5 July 2018

1 reference

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Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

5 July 2018

1 reference

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Polycomb group proteins: navigators of lineage pathways led astray in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Role of the polycomb protein EED in the propagation of repressive histone marks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Mechanisms of polycomb gene silencing: knowns and unknowns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Mouse models of human AML accurately predict chemotherapy response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Menin regulates the function of hematopoietic stem cells and lymphoid progenitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

The INK4-ARF (CDKN2A/B) locus in hematopoiesis and BCR-ABL-induced leukemias

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

5 July 2018

1 reference

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

5 July 2018

1 reference

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A model for transmission of the H3K27me3 epigenetic mark

5 July 2018

1 reference

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MLL translocations, histone modifications and leukaemia stem-cell development

5 July 2018

1 reference

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

5 July 2018

1 reference

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Tissue-specific and reversible RNA interference in transgenic mice

5 July 2018

1 reference

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Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

5 July 2018

1 reference

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

5 July 2018

1 reference

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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

5 July 2018

1 reference

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Control of developmental regulators by Polycomb in human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Polycomb complexes repress developmental regulators in murine embryonic stem cells

5 July 2018

1 reference

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The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation

5 July 2018

1 reference

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ID1 and ID2 are retinoic acid responsive genes and induce a G0/G1 accumulation in acute promyelocytic leukemia cells.

5 July 2018

1 reference

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The molecular basis of leukemia

5 July 2018

1 reference

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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

5 July 2018

1 reference

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Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

The polycomb group protein EZH2 is involved in progression of prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Altered Hox expression and segmental identity in Mll-mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

A gene complex controlling segmentation in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102143

Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2012.110

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2012.110

21 January 2018

Identifiers

DOI

10.1038/ONC.2012.110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

27 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22469984%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference