(Q33924454)

30 July 2017

title

Structural properties of HIV integrase. Lens epithelium-derived growth factor oligomers (English)

1 reference

30 July 2017

Frederic Bushman

4

0 references

author name string

Kushol Gupta

1

1 reference

30 July 2017

Tracy Diamond

2

1 reference

30 July 2017

Young Hwang

3

1 reference

30 July 2017

Gregory D Van Duyne

5

1 reference

30 July 2017

language of work or name

English

0 references

publication date

20 April 2010

1 reference

Journal of Biological Chemistry

30 July 2017

published in

1 reference

30 July 2017

volume

285

1 reference

30 July 2017

issue

26

1 reference

30 July 2017

page(s)

20303-20315

1 reference

describes a project that uses

30 July 2017

PyMOL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=PMC2888443

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5 July 2018

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5 July 2018

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5 July 2018

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Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor

5 July 2018

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5 July 2018

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5 July 2018

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Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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An essential role for LEDGF/p75 in HIV integration

5 July 2018

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Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

5 July 2018

1 reference

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The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

5 July 2018

1 reference

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HIV-1 integrase crosslinked oligomers are active in vitro

5 July 2018

1 reference

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Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase

5 July 2018

1 reference

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Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

5 July 2018

1 reference

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5 July 2018

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LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

5 July 2018

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5 July 2018

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LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

5 July 2018

1 reference

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

5 July 2018

1 reference

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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

5 July 2018

1 reference

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DNA binding induces dissociation of the multimeric form of HIV-1 integrase: a time-resolved fluorescence anisotropy study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Determination of domain structure of proteins from X-ray solution scattering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Repair of gaps in retroviral DNA integration intermediates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Calculation of hydrodynamic properties of globular proteins from their atomic-level structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

In vivo analysis of retroviral integrase structure and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Situs: A package for docking crystal structures into low-resolution maps from electron microscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Quantitative in vitro assay for human immunodeficiency virus deoxyribonucleic acid integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Solution structure of the DNA binding domain of HIV-1 integrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Streptokinase is a flexible multi-domain protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888443

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Loop202-208 in avian sarcoma virus integrase mediates tetramer assembly and processing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Multi-resolution anchor-point registration of biomolecular assemblies and their components.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Functional oligomeric state of avian sarcoma virus integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Automated matching of high- and low-resolution structural models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.114413

Constructing HIV-1 integrase tetramer and exploring influences of metal ions on forming integrase-DNA complex

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HIV integrase inhibitors--out of the pipeline and into the clinic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.114413

1 reference

30 July 2017

1 reference

30 July 2017

1 reference