(Q33928427)

30 July 2017

title

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone (English)

1 reference

30 July 2017

author

Constantine A Stratakis

15

object named as

Constantine A Stratakis

1 reference

30 July 2017

6

Madson Q Almeida

1 reference

30 July 2017

Kit Man Tsang

1

1 reference

30 July 2017

Matthew F Starost

2

1 reference

30 July 2017

Maria Nesterova

3

1 reference

30 July 2017

Sosipatros A Boikos

4

1 reference

30 July 2017

Tonya Watkins

5

1 reference

30 July 2017

Michelle Harran

7

1 reference

30 July 2017

Andrew Li

8

1 reference

30 July 2017

Michael T Collins

9

1 reference

30 July 2017

Christopher Cheadle

10

1 reference

30 July 2017

Edward L Mertz

11

1 reference

30 July 2017

Sergey Leikin

12

1 reference

30 July 2017

Lawrence S Kirschner

13

1 reference

30 July 2017

Pamela Robey

14

1 reference

30 July 2017

language of work or name

English

0 references

publication date

26 April 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

107

1 reference

30 July 2017

issue

19

1 reference

30 July 2017

page(s)

8683-8688

1 reference

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Timing, rather than the concentration of cyclic AMP, correlates to osteogenic differentiation of human mesenchymal stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Identification of progenitor cells that contribute to heterotopic skeletogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Endochondral bone tissue engineering using embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Fibrous dysplasia as a stem cell disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Dynamics of signaling by PKA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Reduction in Gsalpha induces osteogenic differentiation in human mesenchymal stem cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Minireview: PRKAR1A: normal and abnormal functions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Developmental regulation of the growth plate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Targeted expression of activated Q227L G(alpha)(s) in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Pluripotential mesenchymal cells repopulate bone marrow and retain osteogenic properties.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Specificity in the cAMP/PKA signaling pathway. Differential expression,regulation, and subcellular localization of subunits of PKA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Cluster analysis and display of genome-wide expression patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

The major catalytic subunit isoforms of cAMP-dependent protein kinase have distinct biochemical properties in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Protein kinase A and hedgehog signaling in Drosophila limb development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Overexpression of Gs alpha protein in the hearts of transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889322

Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

A mouse model for Carney complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Periostin, a novel marker of intramembranous ossification, is expressed in fibrous dysplasia and in c-Fos-overexpressing bone lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Increased expression of the c-fos proto-oncogene in bone from patients with fibrous dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Mutation of the Calpha subunit of PKA leads to growth retardation and sperm dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Overexpression of RII beta regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by site-directed mutation of RII beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Dissection of the Nucleotide and Metal−Phosphate Binding Sites in cAMP-Dependent Protein Kinase†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003680107

Osteochondromyxoma of bone: a congenital tumor associated with lentigines and other unusual disorders

21 January 2018

1 reference

12 December 2020

Role of adenosine-3',5'-monophosphate in the hormonal regulation of bone resorption: studies with cultured fetal bone

1 reference

12 December 2020

Assay of phosphodiesterase with radioactively labeled cyclic 3',5'-AMP as substrate

1 reference

12 December 2020

Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches

1 reference

12 December 2020

8-Cl-cAMP induces truncation and down-regulation of the RI alpha subunit and up-regulation of the RII beta subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells

1 reference

12 December 2020

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation

1 reference

12 December 2020

A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues

1 reference

12 December 2020

Over-expression of BMP4 and BMP5 in a child with axial skeletal malformations and heterotopic ossification: a new syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1003680107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference