(Q33935094)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Heath Ecroyd

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Martin J. Scanlon

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

John Carver

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

7

Stephen P Bottomley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Amy L Robertson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Helen M Saunders

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

19 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

2 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

10424-10429

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation

2 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Single homopolypeptide chains collapse into mechanically rigid conformations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

The structural impact of a polyglutamine tract is location-dependent

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Crystallin proteins and amyloid fibrils

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Monitoring the prevention of amyloid fibril formation by alpha-crystallin. Temperature dependence and the nature of the aggregating species

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Flanking sequences profoundly alter polyglutamine toxicity in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent beta barrel protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Some like it hot: the structure and function of small heat-shock proteins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

The AXH domain adopts alternative folds the solution structure of HBP1 AXH.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

The interaction of the molecular chaperone, alpha-crystallin, with molten globule states of bovine alpha-lactalbumin

28 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

28 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Effects of site-directed mutations on the chaperone-like activity of alphaB-crystallin.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

alpha B-crystallin is present in reactive glia in Creutzfeldt-Jakob disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

alpha B crystallin expression in non-lenticular tissues and selective presence in ubiquitinated inclusion bodies in human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

The molecular chaperone, alpha-crystallin, inhibits amyloid formation by apolipoprotein C-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

The interaction of the molecular chaperone alpha-crystallin with unfolding alpha-lactalbumin: a structural and kinetic spectroscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

The selective inhibition of serpin aggregation by the molecular chaperone, alpha-crystallin, indicates a nucleation-dependent specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

The interplay between PolyQ and protein context delays aggregation by forming a reservoir of protofibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{alpha} phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Identification of protein surfaces by NMR measurements with a pramagnetic Gd(III) chelate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Structure validation of the Josephin domain of ataxin-3: conclusive evidence for an open conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

The N-terminal domain of alphaB-crystallin is protected from proteolysis by bound substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Substrate binding site flexibility of the small heat shock protein molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Lens alpha-crystallin: chaperone-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890844

Pathogenic and Non-pathogenic Polyglutamine Tracts Have Similar Structural Properties: Towards a Length-dependent Toxicity Gradient

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Mechanisms of Ataxin-3 Misfolding and Fibril Formation: Kinetic Analysis of a Disease-associated Polyglutamine Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914773107

Temperature‐induced exposure of hydrophobic surfaces and its effect on the chaperone activity of α‐crystallin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20484674

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural alterations of alpha-crystallin during its chaperone action

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20484674

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20484674

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0914773107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484674%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20484674

1 reference