(Q33936354)

English

Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

author name string

Nurith Amitai

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Athina Markou

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

2 April 2010

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

European Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

30 July 2017

639

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1-3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

67-80

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Increased impulsivity and disrupted attention induced by repeated phencyclidine are not attenuated by chronic quetiapine treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Chronic nicotine improves cognitive performance in a test of attention but does not attenuate cognitive disruption induced by repeated phencyclidine administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

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5 July 2018

In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

1 reference

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5 July 2018

The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task

1 reference

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5 July 2018

A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity

1 reference

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5 July 2018

Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors

1 reference

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5 July 2018

The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats

1 reference

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5 July 2018

Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS.

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5 July 2018

Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

1 reference

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5 July 2018

Glutamate as a therapeutic target in psychiatric disorders

1 reference

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5 July 2018

Targeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia

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5 July 2018

Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge

1 reference

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5 July 2018

Cognitive function in schizophrenia. Deficits, functional consequences, and future treatment

1 reference

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5 July 2018

Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268.

1 reference

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5 July 2018

Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment

1 reference

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5 July 2018

The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry

1 reference

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5 July 2018

NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Glutamatergic mechanisms in schizophrenia

1 reference

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5 July 2018

Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

1 reference

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5 July 2018

Cognitive impairment in schizophrenia is the core of the disorder.

1 reference

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5 July 2018

The role of cognition in vocational functioning in schizophrenia.

1 reference

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5 July 2018

The role of glutamate receptors in antipsychotic drug action

1 reference

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5 July 2018

Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine

1 reference

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5 July 2018

LY354740 affects startle responding but not sensorimotor gating or discriminative effects of phencyclidine

1 reference

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5 July 2018

Varieties of impulsivity

1 reference

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5 July 2018

The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia

1 reference

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5 July 2018

1 reference

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5 July 2018

Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats.

1 reference

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5 July 2018

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

2-substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioavailability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Schizophrenia and glutamatergic transmission

1 reference

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5 July 2018

Cognitive function in schizophrenia--do neuroleptics make a difference?

1 reference

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5 July 2018

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Dissociating executive functions of the prefrontal cortex.

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5 July 2018

Excessive serotonin release, not depletion, leads to memory impairments in rats.

1 reference

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5 July 2018

The behavioral and neurochemical effects of phencyclidine in humans and animals: some implications for modeling psychosis

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5 July 2018

The phencyclidine-glutamate model of schizophrenia.

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5 July 2018

Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Glutamate receptor dysfunction and schizophrenia

1 reference

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5 July 2018

Phencyclidine (PCP): some human studies

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5 July 2018

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1 reference

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5 July 2018

Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory

1 reference

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5 July 2018

Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence

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5 July 2018

Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia

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5 July 2018

Cognitive inflexibility and pre-frontal dysfunction in schizophrenia and mania

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5 July 2018

Cognitive functioning and symptomatology in chronic schizophrenia

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5 July 2018

Interactions of phencyclidine receptor agonist MK-801 with dopaminergic system: regional studies in the rat.

1 reference

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5 July 2018

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1 reference

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5 July 2018

Recent advances in the phencyclidine model of schizophrenia

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5 July 2018

MK-801 increases extracellular 5-hydroxytryptamine in rat hippocampus and striatum in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Desmethylimipramine attenuates cocaine withdrawal in rats

1 reference

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5 July 2018

Mechanism of the antipsychotic effect in the treatment of acute schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

5 July 2018

Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Cognitive-disruptive effects of the psychotomimetic phencyclidine and attenuation by atypical antipsychotic medications in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Effects of the mGluR2/3 agonist LY379268 on ketamine-evoked behaviours and neurochemical changes in the dentate gyrus of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Cognitive effects of dopaminergic and glutamatergic blockade in nucleus accumbens in pigeons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Assessment of sustained attention in ad libitum fed Wistar rats: effects of MK-801.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Performance of male C57BL/6J mice and Wistar rats in the water maze following various schedules of phencyclidine treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: reversal by the mGLU(2/3) receptor agonist LY379268.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Clozapine treatment attenuated somatic and affective signs of nicotine and amphetamine withdrawal in subsets of rats exhibiting hyposensitivity to the initial effects of clozapine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

The effects of neuroleptics on neuropsychological test results of schizophrenics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Different roles of group I and group II metabotropic glutamate receptors on phencyclidine-induced dopamine release in the rat prefrontal cortex

1 reference

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29 October 2018

The group II metabotropic glutamate receptor agonist (-)-2-oxa-4-aminobicyclo[3.1.0.]hexane-4,6-dicarboxylate (LY379268) and clozapine reverse phencyclidine-induced behaviors in monoamine-depleted rats

1 reference

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29 October 2018

Effects of the mGlu2/3 receptor agonist LY379268 on motor activity in phencyclidine-sensitized rats

1 reference

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29 October 2018

A simple procedure for assessing ataxia in rats: effects of phencyclidine

1 reference

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29 October 2018

Effect of clozapine, haloperidol, or M100907 on phencyclidine-activated glutamate efflux in the prefrontal cortex

1 reference

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29 October 2018

Abnormal kainate receptor expression in prefrontal cortex in schizophrenia

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29 October 2018

The prevalence and stability of an executive processing deficit, response inhibition, in people with chronic schizophrenia.

1 reference

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29 October 2018

Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists.

1 reference

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29 October 2018

Visual attention task performance in Wistar and Lister hooded rats: response inhibition deficits after medial prefrontal cortex lesions.

1 reference

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29 October 2018

Intra-striatal phencyclidine inhibits N-methyl-D-aspartic acid-stimulated increase in glutamate levels of freely moving rats.

1 reference

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29 October 2018

Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism.

1 reference

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29 October 2018

Non-NMDA excitatory amino acid receptors in the ventral tegmental area mediate systemic dizocilpine (MK-801) induced hyperlocomotion and dopamine release in the nucleus accumbens.

1 reference

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29 October 2018

Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task.

1 reference

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29 October 2018

Effects of D-amphetamine and phencyclidine on behavior and extracellular concentrations of neurotensin and dopamine in the ventral striatum and the medial prefrontal cortex of the rat.

1 reference

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29 October 2018

Effect of phencyclidine on dopamine release in the rat prefrontal cortex; an in vivo microdialysis study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

In vivo effects of local and systemic phencyclidine on the extracellular levels of catecholamines and transmitter amino acids in the dorsolateral striatum of anaesthetized rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891116

29 October 2018

Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal.

1 reference

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29 October 2018

Regional effects of MK-801 on dopamine and its metabolites studied by in vivo microdialysis

1 reference

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29 October 2018

The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of clozapine and its metabolite, N-desmethylclozapine, in serum microsamples by high-performance liquid chromatography and its application to pharmacokinetics in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic phencyclidine administration is associated with increased dopamine, GABA, and 5-HIAA levels in the dorsolateral striatum of conscious rats: an in vivo microdialysis study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in performance in three strains of rats in a 5-choice serial reaction time task

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EJPHAR.2009.12.040

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

0 references

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