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Development of second generation EP2 antagonists with high selectivity
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
24937185
retrieved
30 July 2017
title
Development of second generation EP2 antagonists with high selectivity
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
24937185
retrieved
30 July 2017
author
Jianxiong Jiang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
Raymond Dingledine
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
Thota Ganesh
series ordinal
1
object named as
Thota Ganesh
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
publication date
3 June 2014
1 reference
stated in
Europe PubMed Central
PubMed ID
24937185
retrieved
30 July 2017
published in
European Journal of Medicinal Chemistry
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
volume
82
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
page(s)
521-535
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
cites work
Lead optimization studies of cinnamic amide EP2 antagonists
1 reference
stated in
PubMed Central
reference URL
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5 July 2018
Prostanoid receptor EP2 as a therapeutic target
1 reference
stated in
PubMed Central
reference URL
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retrieved
5 July 2018
Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
EP2 receptor signaling pathways regulate classical activation of microglia.
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stated in
PubMed Central
reference URL
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5 July 2018
Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation.
1 reference
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PubMed Central
reference URL
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5 July 2018
Subclinical increased anterior stromal reflectivity with topical taprenepag isopropyl
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5 July 2018
Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2.
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PubMed Central
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5 July 2018
Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus
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PubMed Central
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5 July 2018
A phase 2, randomized, dose-response trial of taprenepag isopropyl (PF-04217329) versus latanoprost 0.005% in open-angle glaucoma and ocular hypertension
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PubMed Central
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5 July 2018
In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP₂ receptor antagonist
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Effect of PF-04217329 a prodrug of a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.
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PubMed Central
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5 July 2018
The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis
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PubMed Central
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5 July 2018
EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities
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5 July 2018
Drug-protein adducts: an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development
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5 July 2018
EP2 and EP4 prostanoid receptor signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Prostanoid receptors: subtypes and signaling
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Prostanoid receptors: structures, properties, and functions
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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29 October 2018
Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
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5 July 2018
Prostanoid receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
COX-2-derived prostacyclin confers atheroprotection on female mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108197
retrieved
29 October 2018
The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24937185
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24937185
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.EJMECH.2014.05.076
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
PMCID
4108197
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
PubMed ID
24937185
1 reference
stated in
Europe PubMed Central
PMCID
4108197
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24937185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
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