(Q33942366)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

Human Induced Pluripotent Stem Cells

1 reference

1 reference

corrigendum / erratum

Author Correction: Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells

1 reference

Chen Chen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Peng Jiang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Haipeng Xue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Suzanne E Peterson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Ha T Tran

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Anna E McCann

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Mana M Parast

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Shenglan Li

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

David E Pleasure

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Ying Liu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Wenbin Deng

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

language of work or name

English

0 references

publication date

18 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

4430

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4109022/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms5430

0 references

cites work

Generation and characterization of spiking and nonspiking oligodendroglial progenitor cells from embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Translating dosage compensation to trisomy 21

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Deficits in human trisomy 21 iPSCs and neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Emerging roles of astrocytes in neural circuit development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

A human stem cell model of early Alzheimer's disease pathology in Down syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Teratoma generation in the testis capsule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Defining the nature of human pluripotent stem cell progeny

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

A bioinformatic assay for pluripotency in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Fragile X astrocytes induce developmental delays in dendrite maturation and synaptic protein expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Nonneuronal cells regulate synapse formation in the vestibular sensory epithelium via erbB-dependent BDNF expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Prospects for minocycline neuroprotection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Thrombospondin 1--a key astrocyte-derived neurogenic factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Electrophysiological properties of human induced pluripotent stem cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Uniquely hominid features of adult human astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Dividing glial cells maintain differentiated properties including complex morphology and functional synapses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Expression profiling of human glial precursors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Modulation of neuritogenesis by astrocyte muscarinic receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Genomic and functional profiling of human Down syndrome neural progenitors implicates S100B and aquaporin 4 in cell injury.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Control of synapse number by glia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: implications for Alzheimer's disease and Down's syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

An inhibitor of neurite outgrowth produced by astrocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Vimentin, the 57 000 molecular weight protein of fibroblast filaments, is the major cytoskeletal component in immature glia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Maturation of astrocytes in vitro alters the extent and molecular basis of neurite outgrowth.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Vitronectin and thrombospondin promote retinal neurite outgrowth: developmental regulation and role of integrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109022

Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Integration-free induced pluripotent stem cells model genetic and neural developmental features of down syndrome etiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Manganese inhibits the ability of astrocytes to promote neuronal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Astronomy: Clue to an ancient cosmic-ray event?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

CNS synaptogenesis promoted by glia-derived cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Thrombospondin 1 accelerates synaptogenesis in hippocampal neurons through neuroligin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Identification of integrin alpha 3 beta 1 as a neuronal thrombospondin receptor mediating neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

OLIG gene targeting in human pluripotent stem cells for motor neuron and oligodendrocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Minocycline prevents cholinergic loss in a mouse model of Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Evidence for apoptosis in the fetal Down syndrome brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5430

Bone morphogenetic proteins induce differentiation in astrocyte lineage cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25034944

12 December 2020

inferred from PubMed ID database lookup

CD44 expression identifies astrocyte-restricted precursor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25034944

12 December 2020

inferred from PubMed ID database lookup

S100beta induces neuronal cell death through nitric oxide release from astrocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25034944

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS5430

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 March 2020

ADS bibcode

2014NatCo...5.4430C

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

25034944

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25034944%20AND%20SRC:MED&resulttype=core&format=json