(Q33950143)

English

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination (English)

1 reference

Europe PubMed Central

30 July 2017

author name string

Chen X

1

1 reference

Europe PubMed Central

30 July 2017

Kinoshita K

2

1 reference

Europe PubMed Central

30 July 2017

Honjo T

3

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

1 November 2001

1 reference

Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

30 July 2017

98

1 reference

Europe PubMed Central

30 July 2017

13860-13865

1 reference

Europe PubMed Central

30 July 2017

24

1 reference

Europe PubMed Central

30 July 2017

Quantitative regulation of class switch recombination by switch region transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Linking class-switch recombination with somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

DNA breaks in hypermutating immunoglobulin genes: evidence for a break-and-repair pathway of somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Increased transcription levels induce higher mutation rates in a hypermutating cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Palindromic but not G-rich sequences are targets of class switch recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Unique and unprecedented recombination mechanisms in class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Processing of switch transcripts is required for targeting of antibody class switch recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Ku80 is required for immunoglobulin isotype switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Frequent but biased class switch recombination in the S mu flanking regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

DNA sequences at immunoglobulin switch region recombination sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Rearrangement of immunoglobulin heavy chain genes during B-lymphocyte development as revealed by studies of mouse plasmacytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Nucleotide sequences of switch regions of immunoglobulin C epsilon and C gamma genes and their comparison

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Nucleotide sequence analysis of the C.AKR Lyt-2a gene: structural polymorphism in alleles encoding the Lyt-2.1 T-cell surface alloantigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Structure of the human interleukin-2 receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Circular DNA is excised by immunoglobulin class switch recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Circular DNA is a product of the immunoglobulin class switch rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

pEF-BOS, a powerful mammalian expression vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Organization of immunoglobulin heavy chain genes and allelic deletion model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

5 July 2018

Deletions in the constant region locus can account for switches in immunoglobulin heavy chain expression

2 references

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/11717442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA sequences mediating class switching in alpha-immunoglobulins.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

Molecular mechanism of immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin gamma 2b-chain gene.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

2 references

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/11717442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic hypermutation in the heavy chain locus correlates with transcription.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

Somatic hypermutation of human immunoglobulin heavy chain genes: targeting of RGYW motifs on both DNA strands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61132

29 October 2018

Deletion of immunoglobulin heavy chain genes from expressed allelic chromosome

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241524898

21 January 2018

Somatic hypermutation of VkappaJkappa rearrangements: targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11717442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of the chicken immunoglobulin heavy-chain constant region gene locus reveals an inverted alpha gene upstream of a condensed upsilon gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/11717442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Switch transcripts in immunoglobulin class switching

1 reference

https://pubmed.ncbi.nlm.nih.gov/11717442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11717442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.241524898

1 reference

Europe PubMed Central

30 July 2017

2001PNAS...9813860C

0 references

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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