Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q33965717)
Watch
English
Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
title
Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
main subject
cooperation
1 reference
based on heuristic
inferred from title
author
Dale A Ramsden
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
author name string
Rika Kusumoto-Matsuo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
Patricia L Opresko
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
Hidetoshi Tahara
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
Vilhelm A Bohr
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
publication date
1 May 2010
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
published in
Aging
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
page(s)
274-284
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
cites work
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Werner Syndrome, aging and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
G-tail telomere HPA: simple measurement of human single-stranded telomeric overhangs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Shelterin: the protein complex that shapes and safeguards human telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Molecular biology of Werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Essential role of limiting telomeres in the pathogenesis of Werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Functional interaction between DNA-PKcs and telomerase in telomere length maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Werner's syndrome: from clinics to genetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Ku complex interacts with and stimulates the Werner protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Ku recruits the XRCC4-ligase IV complex to DNA ends
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Functional and physical interaction between WRN helicase and human replication protein A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Mammalian telomeres end in a large duplex loop
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Bloom's syndrome gene product is a 3'-5' DNA helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
The Werner syndrome protein is a DNA helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Recombinant replication protein A: expression, complex formation, and functional characterization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Genetics and aging; the Werner syndrome as a segmental progeroid syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
5 July 2018
Werner syndrome protein contains three structure-specific DNA binding domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
29 October 2018
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898018
retrieved
29 October 2018
Identifiers
DOI
10.18632/AGING.100141
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
PMCID
2898018
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
PubMed ID
20519774
1 reference
stated in
Europe PubMed Central
PMCID
2898018
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519774%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
