(Q33966887)

30 July 2017

title

Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination (English)

1 reference

30 July 2017

S B Kale

1

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30 July 2017

M A Landree

series ordinal

2

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30 July 2017

D B Roth

series ordinal

3

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30 July 2017

language of work or name

English

0 references

publication date

1 January 2001

1 reference

Molecular and Cellular Biology

30 July 2017

published in

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30 July 2017

volume

21

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30 July 2017

issue

2

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30 July 2017

page(s)

459-466

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describes a project that uses

30 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC86598/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

28 July 2018

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RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

28 July 2018

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28 July 2018

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28 July 2018

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The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step

28 July 2018

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V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

28 July 2018

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Functional analysis of coordinated cleavage in V(D)J recombination

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

28 July 2018

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RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

28 July 2018

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A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

28 July 2018

1 reference

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RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

28 July 2018

1 reference

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DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences

28 July 2018

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Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

28 July 2018

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Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage

28 July 2018

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Genetic evidence that the RAG1 protein directly participates in V(D)J recombination through substrate recognition

28 July 2018

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The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

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28 July 2018

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Initiation of V(D)J recombination in vitro obeying the 12/23 rule

28 July 2018

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Expression and V(D)J recombination activity of mutated RAG-1 proteins

28 July 2018

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28 July 2018

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The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

28 July 2018

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Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

28 July 2018

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The role of metal ions in the conformation of the four-way DNA junction.

28 July 2018

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Structural aspects of a higher order nucleoprotein complex: induction of an altered DNA structure at the Mu-host junction of the Mu type 1 transpososome

28 July 2018

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28 July 2018

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

28 July 2018

1 reference

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Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

Initiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

Disruption of the terminal base pairs of retroviral DNA during integration

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

Initiation of V(D)J recombination in a cell-free system.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

Base-pairing shift in the major groove of (CA)n tracts by B-DNA crystal structures

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86598

Novel strand exchanges in V(D)J recombination

29 October 2018

1 reference

12 December 2020

Cell-free V(D)J recombination

1 reference

12 December 2020

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

1 reference

12 December 2020

Coding joint formation in a cell-free V(D)J recombination system

1 reference

12 December 2020

10.1128/MCB.21.2.459-466.2001

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference