(Q33977490)

30 July 2017

title

Structural basis of transmembrane domain interactions in integrin signaling (English)

1 reference

30 July 2017

main subject

transmembrane protein

0 references

author name string

Tobias S Ulmer

series ordinal

1

1 reference

30 July 2017

publication date

10 April 2010

1 reference

Cell Adhesion and Migration

30 July 2017

published in

1 reference

30 July 2017

volume

4

1 reference

30 July 2017

issue

2

1 reference

30 July 2017

page(s)

243-248

1 reference

Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation

30 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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Multiple approaches converge on the structure of the integrin alphaIIb/beta3 transmembrane heterodimer

5 July 2018

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The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

5 July 2018

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The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

5 July 2018

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Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation

5 July 2018

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Linking integrin conformation to function

5 July 2018

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Integrin signalling at a glance

5 July 2018

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Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

5 July 2018

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Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunits

5 July 2018

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Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins

5 July 2018

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Spatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1

5 July 2018

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Structural studies of the transmembrane C-terminal domain of the amyloid precursor protein (APP): does APP function as a cholesterol sensor?

5 July 2018

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Computationally designed peptide inhibitors of protein-protein interactions in membranes

5 July 2018

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Structure of the Integrin IIb Transmembrane Segment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Integrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Permissive transmembrane helix heterodimerization is required for the expression of a functional integrin.

5 July 2018

1 reference

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Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger

5 July 2018

1 reference

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The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor

5 July 2018

1 reference

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5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

A push-pull mechanism for regulating integrin function

5 July 2018

1 reference

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A specific interface between integrin transmembrane helices and affinity for ligand

5 July 2018

1 reference

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Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits

5 July 2018

1 reference

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New insights into the structural basis of integrin activation.

5 July 2018

1 reference

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The structure and thermal motion of the B800-850 LH2 complex from Rps.acidophila at 2.0A resolution and 100K: new structural features and functionally relevant motions

5 July 2018

1 reference

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Integrins: bidirectional, allosteric signaling machines

5 July 2018

1 reference

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

5 July 2018

1 reference

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Transmembrane signal transduction of the alpha(IIb)beta(3) integrin

5 July 2018

1 reference

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Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

5 July 2018

1 reference

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The phosphotyrosine binding-like domain of talin activates integrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Crystal structure of the extracellular segment of integrin alpha Vbeta3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

A transmembrane helix dimer: structure and implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Integrin cytoplasmic domains mediate inside-out signal transduction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900621

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

5 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Bilayer in small bicelles revealed by lipid-protein interactions using NMR spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

A new look at the lipid composition of the plasma membrane of human blood platelets relative to the GPIIb/IIIa (integrin cxIIβ3) content

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Membrane-proximal {alpha}/{beta} stalk interactions differentially regulate integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Atomic-scale structure and electrostatics of anionic palmitoyloleoylphosphatidylglycerol lipid bilayers with Na+ counterions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Determination of the Border between the Transmembrane and Cytoplasmic Domains of Human Integrin Subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCAM.4.2.10592

Unambiguous prediction of human integrin transmembrane heterodimer interactions using only homologous sequences

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20168080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The transmembrane structure of integrin alphaIIbbeta3: significance for signal transduction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20168080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CAM.4.2.10592

1 reference

30 July 2017

1 reference

30 July 2017

1 reference