(Q33979376)

30 July 2017

Sirolimus therapy to halt the progression of ADPKD. (English)

1 reference

30 July 2017

1 reference

Bogdan Ene-Iordache

19

0 references

Andrea Remuzzi

Andrea Remuzzi

20

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Giuseppe Remuzzi

Giuseppe Remuzzi

21

0 references

Piero Ruggenenti

4

Piero Ruggenenti

1 reference

30 July 2017

17

Monica Cortinovis

1 reference

30 July 2017

Anna Caroli

3

0 references

Olimpia Diadei

9

Olimpia Diadei

1 reference

30 July 2017

14

Sergio Carminati

1 reference

30 July 2017

1

Norberto Perico

1 reference

30 July 2017

6

Mariateresa Cafaro

1 reference

30 July 2017

5

Giorgio Fasolini

1 reference

30 July 2017

7

Patrizia Ondei

1 reference

30 July 2017

8

Nadia Rubis

1 reference

30 July 2017

11

Silvia Prandini

1 reference

30 July 2017

16

Flavio Gaspari

1 reference

30 July 2017

18

Nicola Motterlini

1 reference

30 July 2017

13

Rodolfo Flores Bravo

1 reference

30 July 2017

Luca Antiga

2

1 reference

30 July 2017

Giulia Gherardi

10

1 reference

30 July 2017

Andrea Panozo

12

1 reference

30 July 2017

Felipe Rodriguez De Leon

15

1 reference

30 July 2017

language of work or name

1 reference

13 May 2010

1 reference

Journal of the American Society of Nephrology

30 July 2017

1 reference

30 July 2017

21

1 reference

30 July 2017

1031-1040

1 reference

30 July 2017

6

1 reference

describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2900967/fullTextXML

inferred from PubMed Central ID database lookup

cites work

2008 Homer W. Smith Award: insights into the pathogenesis of polycystic kidney disease from gene discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Mammalian target of rapamycin inhibitor dyslipidemia in kidney transplant recipients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Sirolimus reduces polycystic liver volume in ADPKD patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

5 July 2018

The two TORCs and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

TRPP2 and autosomal dominant polycystic kidney disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

TOR signaling in growth and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Rapamycin is an effective inhibitor of human renal cancer metastasis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Regulation of translation initiation by FRAP/mTOR

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Renal accumulation and excretion of cyclic adenosine monophosphate in a murine model of slowly progressive polycystic kidney disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

The renin-angiotensin-aldosterone system and autosomal dominant polycystic kidney disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Safety and tolerability of sirolimus treatment in patients with autosomal dominant polycystic kidney disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Improving clinical trial design for inquiries into the mechanisms of cyst growth in ADPKD.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Proliferation signal inhibitor-induced decrease of vascular endothelial cadherin expression and increase of endothelial permeability in vitro are prevented by an anti-oxidant

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Sirolimus as primary immunosuppressant reduces left ventricular mass and improves diastolic function of the cardiac allograft

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Computed tomography evaluation of autosomal dominant polycystic kidney disease progression: a progress report.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Safety and efficacy of long-acting somatostatin treatment in autosomal-dominant polycystic kidney disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Assessment of sirolimus concentrations in whole blood by high-performance liquid chromatography with ultraviolet detection

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900967

Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist

29 October 2018

1 reference

12 December 2020

Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease

1 reference

12 December 2020

New antitumor substances of natural origin

1 reference

12 December 2020

Growth factor gene expression in kidney of murine polycystic kidney disease

1 reference

12 December 2020

Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells

1 reference

12 December 2020

Volume progression in polycystic kidney disease

1 reference

12 December 2020

Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2009121302

1 reference

30 July 2017

1 reference

30 July 2017

1 reference