(Q33984365)

30 July 2017

title

Comprehensive bioinformatic analysis of the specificity of human immunodeficiency virus type 1 protease (English)

1 reference

30 July 2017

1 reference

Liwen You

1

1 reference

30 July 2017

Daniel Garwicz

series ordinal

2

1 reference

30 July 2017

Thorsteinn Rögnvaldsson

series ordinal

3

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30 July 2017

language of work or name

English

0 references

publication date

1 October 2005

1 reference

30 July 2017

number of pages

10

1 reference

inferred from page(s)

published in

Journal of Virology

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30 July 2017

volume

79

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30 July 2017

issue

19

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30 July 2017

page(s)

12477-12486

1 reference

Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites

30 July 2017

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5 July 2018

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5 July 2018

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Positive selection detection in 40,000 human immunodeficiency virus (HIV) type 1 sequences automatically identifies drug resistance and positive fitness mutations in HIV protease and reverse transcriptase

5 July 2018

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5 July 2018

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Variability at human immunodeficiency virus type 1 subtype C protease cleavage sites: an indication of viral fitness?

5 July 2018

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5 July 2018

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5 July 2018

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Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease

5 July 2018

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5 July 2018

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Changes in human immunodeficiency virus type 1 Gag at positions L449 and P453 are linked to I50V protease mutants in vivo and cause reduction of sensitivity to amprenavir and improved viral fitness in vitro

5 July 2018

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Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes

5 July 2018

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Altered substrate specificity of drug-resistant human immunodeficiency virus type 1 protease

5 July 2018

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HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation

5 July 2018

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Molecular basis for the relative substrate specificity of human immunodeficiency virus type 1 and feline immunodeficiency virus proteases

5 July 2018

1 reference

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Local and spatial factors determining HIV-1 protease substrate recognition

5 July 2018

1 reference

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Human immunodeficiency virus type 1 protease cleavage site mutations associated with protease inhibitor cross-resistance selected by indinavir, ritonavir, and/or saquinavir

5 July 2018

1 reference

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Identification of efficiently cleaved substrates for HIV-1 protease using a phage display library and use in inhibitor development

5 July 2018

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5 July 2018

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Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites

5 July 2018

1 reference

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5 July 2018

1 reference

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Prediction of human immunodeficiency virus protease cleavage sites in proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Human immunodeficiency virus, type 1 protease substrate specificity is limited by interactions between substrate amino acids bound in adjacent enzyme subsites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Inhibition of HIV infection by pseudopeptides blocking viral envelope glycoprotein-mediated membrane fusion and cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles.

5 July 2018

1 reference

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5 July 2018

1 reference

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Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins

5 July 2018

1 reference

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Studies on the role of the S4 substrate binding site of HIV proteinases

5 July 2018

1 reference

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A cumulative specificity model for proteases from human immunodeficiency virus types 1 and 2, inferred from statistical analysis of an extended substrate data base

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies

5 July 2018

1 reference

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Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Narrow substrate specificity and sensitivity toward ligand-binding site mutations of human T-cell Leukemia virus type 1 protease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Why neural networks should not be used for HIV-1 protease cleavage site prediction.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Bio-support vector machines for computational proteomics

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Searching for discrimination rules in protease proteolytic cleavage activity using genetic programming with a min-max scoring function.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Characterizing proteolytic cleavage site activity using bio-basis function neural networks

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Effect of sequence polymorphism and drug resistance on two HIV-1 Gag processing sites.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Support Vector Machines for predicting HIV protease cleavage sites in protein.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Comparison of the substrate specificity of the human T-cell leukemia virus and human immunodeficiency virus proteinases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1211560

Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16160175

12 December 2020

inferred from PubMed ID database lookup

Studies on the symmetry and sequence context dependence of the HIV-1 proteinase specificity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16160175

12 December 2020

inferred from PubMed ID database lookup

Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16160175

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/JVI.79.19.12477-12486.2005

1 reference

30 July 2017

1 reference

30 July 2017

1 reference